Clinical Report
Clinical study on treatment of endometriosis dysmenorrhea with Qingyu Wentong method
Yang Cao, Lulu Tian, Lei Weng, Landi Shu, Tingting Zhang
Published 2019-02-25
Cite as Chin J Reprod Contracep, 2019, 39(2): 130-134. DOI: 10.3760/cma.j.issn.2096-2916.2019.02.009
Abstract
ObjectiveTo observe the clinical efficacy of Qingyu Wentong method in treating endometriosis (EMS) dysmenorrhea.
MethodsNinty-one cases of EMS patients were randomly divided into two groups, 45 cases in treatment group and 46 cases in control group. The treatment group was given Qingyu Wentong formula and control group was given placebo. All patients were continuously treated for 3 menstrual cycles. The dysmenorrhea, traditional Chinese medicine (TCM) symptom effect, serum CA125 and prostaglandin E2 (PGE2) were observed and analyzed statistically. And the quality of life was assessed by the Endometriosis Health Profile-30 (EHP-30) in two groups.
ResultsThe remission rate of dysmenorrhea was 82.2% and 23.9%, respectively (P<0.001). After treatment, dysmenorrhea scale scores of two groups were lower than before treatment (P<0.001), and the treatment group was superior to control group (P=0.037). The total effective rates of TCM syndromes in treatment group and control group were 80.0% and 30.4%, respectively. After treatment, the scores of TCM syndromes in both groups were significantly improved (P<0.001), and there was a significant difference between the two groups (P=0.044). After treatment, the CA125 [(41.50±34.85) U/mL] and PGE2 values [(350.52±125.98) ng/L] in the treatment group decreased (P<0.001), and treatment group was better than control group (P<0.001). Two groups of patients’ quality of life was improved. There was a significant difference in pain control, emotional stability and social support between the two groups (P<0.001).
ConclusionQingyu Wentong method can reduce the degree of dysmenorrhea in EMS patients, reduce the levels of CA125 and PGE2, improve the quality of life and clinical efficacy. It is worthy of recommendation.
Key words:
Endometriosis; Quality of life; Qingyu Wentong method; Dysmenorrheal
Contributor Information
Yang Cao
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
Lulu Tian
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
Lei Weng
Shanghai First Maternity and Infant Hospital, Shanghai 200040, China
Landi Shu
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China
Tingting Zhang
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
