Review
Application progress of recombinant human growth hormone in assisted reproductive technology
Xiaolin Wu, Lingling Huang, Lei Liang, Ping Li
Published 2020-03-25
Cite as Chin J Reprod Contracep, 2020, 40(3): 241-245. DOI: 10.3760/cma.j.cn101441-20190315-00099
Abstract
In order to improve the outcome of in vitro fertilization-embryo transfer (IVF-ET) treatment, recombinant human growth hormone (rhGH) has been widely used in assisted reproductive technology (ART), and has obvious improvement in patients with ovarian dysfunc-tion, such as diminished ovarian reserve (DOR), poor ovarian response (POR), polycystic ovary syndrome (PCOS), and abnormal endometrium patients such as repeated implantation failed (RIF), thin endometrium and intrauterine adhesions (IUA). But there is no unified standard about the target patients and application protocol of rhGH. This paper summarizes the mechanism and usage of rhGH in the above patients.
Key words:
Fertilization in vitro; Embryo transfer; Reproductive techniques, assisted; Recombinant human growth hormone; Ovarian dysfunction; Abnormal endometrium
Contributor Information
Xiaolin Wu
Women and Children’s Hospital Affiliated to Xiamen University (Xiamen Maternal and Child Care Hospital), Xiamen 361003, China
Lingling Huang
Women and Children’s Hospital Affiliated to Xiamen University (Xiamen Maternal and Child Care Hospital), Xiamen 361003, China
Lei Liang
Women and Children’s Hospital Affiliated to Xiamen University (Xiamen Maternal and Child Care Hospital), Xiamen 361003, China
Ping Li
Women and Children’s Hospital Affiliated to Xiamen University (Xiamen Maternal and Child Care Hospital), Xiamen 361003, China