By analyzing the present development and reform experiments for public hospitals in Shenzhen,the author proposed the following directions for such a reform:1) Accelerating steps of the development strategy "One Large and One Small",to achieve a balanced deployment of local healthcare resources;2) Building a public hospitals group with reasonable resources deployment and information resources sharing;3) Advancing reforms of public hospitals,building an administrative system of public hospitals featuring separation between government functions and hospitals operations and that between hospital administration and hospital building;4) Improving the supervision mechanism for public hospitals featuring distinct rights and responsibilities and powerful regulatory practice;5) Building a scientific operation system of efficient incentives and self constraints;6) Building a service model for public hospitals featuring separation of medical service and pharmaceuticals sales and normalized system.