Effectiveness analysis and inspirations of rational administration of carbapenem
Yan Zhang, Mengjie Wang, Yin Xu, Xiaozhou He, Fei Hua, Jun Zhou, Yuyue Wang, Chunyan Qian, Lifei Yang, Li Li, Bin Wang, Keye Tao, Ling Yang
Published 2018-04-02
Cite as Chin J Hosp Admin, 2018, 34(4): 310-314. DOI: 10.3760/cma.j.issn.1000-6672.2018.04.012
Abstract
The hospital introduced a multi-department synergy in management of the rational use of carbapenems. Specifically, the medical affairs department conducts training and appraisal of doctors along with a monthly checkup of medical records. The pharmaceutical affairs division conducts prior prescriptions checkup and follow-up comment. The clinical microbiology laboratory and the hospital-acquired infection management department monitors and releases such infection and bacterial resistance information of the whole hospital in real time. The results showed increased prescriptions of imipenem and cilastatin sodium, and decreased prescriptions of biapenem for injection. Drug resistance analysis showed that carbapenem resistant strains increased by 28%, but the total number of patients reduced by 10% and total number of patients with multidrug resistance remained unchanged. It is proposed to further antimicrobial stewardship in the hospital to achieve rational drug use and curb bacterial resistance.
Key words:
Pharmacy administration; Carbapenem; Antibacterial agent; Rational use
Contributor Information
Yan Zhang
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Mengjie Wang
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Yin Xu
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Xiaozhou He
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Fei Hua
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Jun Zhou
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Yuyue Wang
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Chunyan Qian
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Lifei Yang
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Li Li
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
Bin Wang
Keye Tao
Ling Yang
First People′s Hospital of Changzhou, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
