Objective To study the clinical characteristics of tumors at the place between pons and oblongata,the methods of microsurgical treatment,and treatment for complications of microsurgery.Methods The 23 patients undergoing surgical treatment of tumors originated from pons and medullary were reviewed retrospectively.Preoperative clinical presentation and lesion characteristics,adopted surgical approach and complications were analyzed.Results All cases in this group were accepted microsurgical treatment.Numbers of total resection,subtotal resection,and partial resection of tumors were 15,4 and 4,respectively.Cases of glioma,cavernous malformation,hemangioblastoma,and lymphoma were 15,3,4 and 1,respectively.Perioperative complications of worsening original symptoms,new neurological symptoms,intracranial infection,and neurogenic pulmonary edema and bulbar paralysis occupied 6,4,1,1,respectively.There was no death in perioperative.Conclusions There are many kinds of tumors at the place between pons and oblongata,and many patients had severe perioperative complications.Appropriate surgical indications and approaches,microsurgical operation,the prevention and treatment to the postoperative complications,contribute to improve the treatment effect of tumors at the place of pons and oblongata.