Original Article
An analysis of the characteristics of perioperative cardiac troponin elevation in orthopaedic surgical patients
Wenlan Hu, Youzhou Chen, Jihong Wang, Xiaolong Hao, Dongxu Zhai, Huayi Sun, Xingshan Zhao
Published 2018-05-01
Cite as Chin J Intern Med, 2018, 57(5): 340-344. DOI: 10.3760/cma.j.issn.0578-1426.2018.05.007
Abstract
ObjectivePerioperative myocardial infarction remains a severe complication in non-cardiac surgery and is one of the major causes of death. Cardiac troponin (cTn) I elevation is associated with short-term and long-term mortality. The aim of the study was to assess the proportion rate of cTnI elevation and its clinical characteristics among patients admitted for orthopaedic surgery with or without cardiovascular events.
MethodsThis is a retrospective study including 27 744 patients aged 50 years or older who admitted for orthopaedic surgery from 2009-2015 in Beijing Jishuitan Hospital.
ResultsTwo hundred and sixty-five patients [age (71.7±9.9) years] had cTnI level> 0.04 μg/L with 66% (175 patients) of them being female. Among them, 59 patients were isolated troponin rise (ITR) (n=59), 13 were preoperative acute myocardial infarction (AMI), and 193 were postoperative AMI. The proportion of postoperative AMI was 0.69%. Those patients were more likely to have a history of coronary artery disease or hypertension. Non-ST-segment elevation myocardial infarction (NSTEMI) was more common (93.3%) than ST-segment elevation myocardial infarction in these patients. Most of them did not experience ischemic symptoms. Totally 76.7% of the AMI occurred within 3 days of surgery; and the in-hospital mortality rate was 10.4%.
ConclusionsPerioperative elevation of troponin is common in patients undergoing orthopaedic surgery. Most postoperative AMI were NSTEMI and with absent or atypical ischemia symptoms. Monitoring troponin levels and electrocardiograph in at-risk patients is needed to find most of the AMI.
Key words:
Troponin I; Perioperative myocardial infarction; Orthopaedic surgery
Contributor Information
Wenlan Hu
Department of Cardiovascular, Beijing Jishuitan Hospital, The Fourth Medical Clinical Hospital of Peking University, Beijing 100035, China
Youzhou Chen
Jihong Wang
Xiaolong Hao
Dongxu Zhai
Huayi Sun
Xingshan Zhao