Assessment of cardiac morphology and ventricular function in healthy Chinese individuals using MRI
LU Min-jie, ZHAO Shi-hua, JIANG Shi-liang, YIN Gang, ZHANG Yan, LING Jian, LIU Qiong, WEI Yun-qing, YAN Chao-wu, L(U) Jian-hua, QI Xiao-ou, CHENG Huai-bing, MA Ning
Abstract
Objective To investigate reproducibility of cardiac MRI for assessment of cardiac morphology and ventricular function in selected normal Chinese Han population.Methods Two hundred and sixty-nine normal volunteers underwent cardiac MRI using a 1.5 T MR system.HASTE and steady state free precession imaging were performed with long and short axis images and cine mode through the ventricle with wireless vector cardiac gating.The images were reviewed by two independent observers.The dimensions of cardiac chambers and ventricular function including ejection fraction (EF),end diastolic volume( EDV),end systolic volume (ESV) and myocardial mass were evaluated.The data between male and female were compared by using two-tailed unpaired t test.Results Total imaging time was (15 ± 3 ) min.The anteroposterior diameter of the left atrium was( 2.87 ± 0.77 ) cm,the right atrial diameter perpendicular to the atrial septum was ( 3.61 ± 0.57 ) cm,the end diastolic diameter of the left ventricle was (4.97 ±0.52) cm,the end diastolic diameter of the right ventricle was (2.65 ± 0.48) cm.On the left ventricle,EF was(60.62 ±7.08)%,EDV was (115.37 ±26.71) ml,ESV was (46.02+15.72) ml and LV mass was ( 82.97± 24.03 ) g.On the right ventricle,EF was (47.73 ± 6.50 ) %,EDV was ( 128.27 ± 32.16 )ml,ESV was (67.7 ± 21.07) ml and RV mass was (48.24 ± 13.42) g.There were no statistically significant differences in LVESV( P =0.144 ),LVEDV index ( P =0.714 ),LVESV index ( P =0.113 ),LVCI ( P =0.199),RVEF ( P =0.296 ) and RV mass ( P =0.093 ),and statistically significant differences in other cardiac parameters between male and female.Conclusion Cardiac MRI can provide useful information about cardiac function and morphology with a high level of reproducibility in normal Chinese Han population.
Key words:
Ventricular function; Magnetic resonance imaging; Research subjects
Contributor Information
LU Min-jie
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
ZHAO Shi-hua
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
JIANG Shi-liang
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
YIN Gang
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
ZHANG Yan
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
LING Jian
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
LIU Qiong
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
WEI Yun-qing
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
YAN Chao-wu
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
L(U) Jian-hua
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
QI Xiao-ou
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
CHENG Huai-bing
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China
MA Ning
Department of Radiology, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College,Chinese Academy of Medical Sciences, National Center for Cardiovascular Disease, Beijing 100037, China