Original Article
Solumbra thrombectomy as intravascular recanalization for treatment of acute ischemic stroke due to large cerebral artery occlusion
Zhang Heliang, Liu Meili, Sun Gang, Guo Zaiyu, Zhang Wenlong, Gui Qinghong, Li Bo
Published 2018-02-14
Cite as Chin J Geriatr, 2018,37(2): 148-153. DOI: 10.3760/cma.j.issn.0254-9026.2018.02.008
Abstract
ObjectiveTo investigate the feasibility, effectiveness, and technical superiority of Solumbra thrombectomy for treatment of acute large cerebral artery occlusion stroke.
Methods32 patients who had acute large cerebral artery occlusion stroke and received mechanical thrombectomy in TEDA Hospital of Tianjin between January 2013 and August 2016, were divided into two groups: stent group(with conventional stent-retrievers, n=21)and Solumbra group(with Solumbra thrombectomy, n=11). Clinical characteristics, variables correlated with operation, and clinical outcomes were compared and analyzed retrospectively.
ResultsThere were no differences in basic clinical and radiographic parameters between stent group versus Solumbra group(all P>0.05). Moreover, there were no differences between Solumbra group versus Stent group in rates of embolus to new territory(18.2% vs.28.6%, P=0.425), in times of thrombectomy(2.2±1.0 vs.2.4±1.3, P=0.657), in non-symptomatic intracranial hemorrhage(18.2% vs.14.3%, P=0.572), in symptomatic intracranial hemorrhage(18.2% vs.9.5%, P=0.427), in TICI 2b/3 revascularization(81.8% vs.81.0%, P=0.670), in puncture-to-reperfusion time[(66.4±39.0)min vs.(51.6±34.5)min, P=0.279], and in NIHSS at 7 days(11.6±7.7 vs.11.3±7.2, P=0.925). A modified Rankin Scale(mRS ≤2)is a variable of recovery of function and good clinical outcome at 90 days.The levels of mRS were similar(P=0.490)between Solumbra and stent groups, but there was a tendency to higher rate of good clinical outcome at 90 days in Solumbra group(63.6%, 7/11)than in stent group(47.6%, 10/21).
ConclusionsSolumbra thrombectomy as intravascular revascularization technique is an effective and safe strategy for endovascular recanalization of acute large cerebral artery occlusion stroke.Compared with conventional Stent-Retriever thrombectomy, Solumbra thrombectomy has a good clinical outcome tendency at 90 days after operation.
Key words:
Brain infarction; Solumbra technique
Contributor Information
Zhang Heliang
Department of Neurosurgery, TEDA Hospital of Tianjin, Tianjin 300457, China
Liu Meili
Department of Neurology, TEDA Hospital of Tianjin, Tianjin 300457, China
Sun Gang
Department of Neurology, TEDA Hospital of Tianjin, Tianjin 300457, China
Guo Zaiyu
Department of Neurosurgery, TEDA Hospital of Tianjin, Tianjin 300457, China
Zhang Wenlong
Department of Neurosurgery, TEDA Hospital of Tianjin, Tianjin 300457, China
Gui Qinghong
Department of Neurology, TEDA Hospital of Tianjin, Tianjin 300457, China
Li Bo
Department of Neurosurgery, TEDA Hospital of Tianjin, Tianjin 300457, China