Original Article
Analysis of risk factors for in-stent restenosis and reocclusion after coronary stent implantation in advanced-age patients
Zhang Li, Pan Changjiang, Liu Tao, Fang Xiang, Hu Youdong, Zhang Fenglin, Chen Ying, Zhou Hualan, Guo Dianxuan, Li Xia
Published 2018-03-14
Cite as Chin J Geriatr, 2018, 37(3): 260-263. DOI: 10.3760/cma.j.issn.0254-9026.2018.03.004
Abstract
ObjectiveTo investigate risk factors for in-stent restenosis and reocclusion after coronary stent implantation in aged patients.
Methods131 patients diagnosed with chronic total occlusion and old myocardial infarction due to coronary stenosis were recruited in this retrospective study from Mar 2004 to May 2015. Patients were divided into 50 to 59 years old group (n=51), 60 to 69 years old group (n=43), and 70 to 80 years old group (n=37) to study coronary lesion characteristics. In-stent restenosis and reocclusion were detected at 6, 12, 18, and 24 months after coronary stent implantation.
ResultsBefore coronary stent implantation, the incidence rate of type 2 diabetes was significantly increased with three increasing age groups: 9.8% at ages 50-59 group (n=5), 18.6% at ages 60-69 group (n=8), and 27.0% at ages 70-80 group (n=10) (all P<0.01). The incidence rates of multiple coronary artery disease, long coronary lesions (>20 mm), eccentric coronary lesions, serious angle of coronary lesions, irregular coronary lesions, proximal coronary curvature, moderate to severe calcified coronary lesions, coronary restenosis (90%-99% or 100%), and complex bifurcation lesions were significantly elevated with three increasing age groups (P <0.01 or P <0.05). The ratios of patients with in-stent restenosis at 24 months after coronary stent implantation were significantly elevated with three increasing age groups: at 9.8% (n=5), 18.6% (n=8), and 27.0%(n=10) for 90%-99% restenosis sub-group, and at 5.9% (n=3), 14.0% (n=6) and 24.3% (n=9) for 100% restenosis sub-group, respectively (all P<0.05 orP<0.01).
ConclusionsType 2 diabetes is an independent risk factor for complex coronary lesions in aged patients. Complex coronary lesions, three or more stents, and long coronary stents may lead to in-stent restenosis and reocclusion after coronary stent implantation in aged patients.
Key words:
Coronary artery disease; Angioplasty, transluminal, percutaneous coronary; Coronary stenosis
Contributor Information
Zhang Li
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
Pan Changjiang
Jiangsu Key Laboratory for Interventional Medical Devices, Huaian 223003, China
Liu Tao
Jiangsu Key Laboratory for Interventional Medical Devices, Huaian 223003, China
Fang Xiang
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
Hu Youdong
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
Zhang Fenglin
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
Chen Ying
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
Zhou Hualan
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
Guo Dianxuan
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
Li Xia
Department of Geriatrics, Huaian Hospital Affiliated to Xuzhou Medical University, Huaian 223002, China
