Diagnosis and treatment of prostate cancer
Evaluation of MR targeted biopsy for the diagnosis of prostate cancer
Zhipeng Zhang, Ming Liu, Min Chen, Chunmei Li, Xin Wang, Xuan Wang, Ben Wan, Shengcai Zhu, Jianye Wang
Published 2016-03-15
Cite as Chin J Urol, 2016, 37(3): 161-164. DOI: 10.3760/cma.j.issn.1000-6702.2016.03.001
Abstract
ObjectiveTo evaluate the efficacy of MR targeted and transrectal ultrasond guided prostate biopsy for the diagnosis of prostate cancer.
MethodsFrom July 2014 to March 2015, 35 patients underwent MR guided prostate biopsy and 141 patients underwent TRUS guided biopsy were retrospectively evaluated. The MRI results and pathology were analyzed.
ResultsThere were no statistical differences between the two groups in term of age, prostate volume and serum PSA level (P>0.05). The overall positive rate for prostate cancer was 48.3%, with a higher positive rate in MR targeted group (57.1%) compared with TRUS group (46.1%). More patients with high grade prostate cancer were diagnosed by MR targeted biopsy compared with TRUS guided biopsy and statistical significant differences was present in patients with PSA<10 ng/ml.
ConclusionsThe MR targeted biopsy showed a high positive rate for high grade prostate cancer, which is of great value for the prevention of over-diagnosis and overtreatment of prostate cancer.
Key words:
Prostate cancer; Diagnosis; Biopsy
Contributor Information
Zhipeng Zhang
Graduate School of Peking Union Medical College, Beijing Institute of Geriatrics, Ministry of Health, Department of Urology, Beijing Hospital, beijing 100730, China
Ming Liu
Min Chen
Chunmei Li
Xin Wang
Xuan Wang
Ben Wan
Shengcai Zhu
Jianye Wang