Innovative Therapy of Urolithiasis
The analysis of urolithiasis incidence in the contralateral kidney of unilateral nephrectomy patients
Tianpeng Xie, Qingquan Xu, Xiaobo Huang, Xiaofeng Zou, Guoxi Zhang, Liulin Xiong, Kai Ma, Yuanhu Yuan, Rihai Xiao, Xiaoning Wang, Haiyun Ye, Lizhe An
Published 2017-09-15
Cite as Chin J Urol, 2017, 38(9): 683-686. DOI: 10.3760/cma.j.issn.1000-6702.2017.09.011
Abstract
ObjectiveTo analyze the incidence of urinary stone formation in the contralateral kidney of unilateral nephrectomy patients.
Methods1048 patients, including 596 males and 452 females, underwent unilateral nephrectomy from June 2010 to June 2016. Their age ranged from 16-87 years old (mean 58.7 years old).532 patients combined with components of metabolic syndrome and 213 patients with metabolic syndrome.164 patients had a previous history of urolithiasis.The incidence of urinary stone formation in the contralateral kidney after nephrectomy was recorded and analyzed.The urolithiasis incidences in different gender, age, comorbidity and history of urolithiasis patients after uninephrectomy were compared.
ResultsAll patients were followed up within 0.5 to 6 years (mean 3.2 years). 89 patients suffered from urinary stones in the contralateral kidney after uninephrectomy.The incidence of urinary stone formation in the contralateral kidney was 8.5%(89/1048), which was higher than that in general population of China. 1%-5%.The urolithiasis incidence was 9.1%(54/596)in male patients and 7.7%(35/452)in female patients after nephrectomy. The incidence of urinary stone formation was 8.6%(3/35)in patients aged under 30 years old, 12.5%(34/272)in patients aged 30-49 years old, 7.3%(37/504)in patients aged 50-69 years old, 6.3%(15/237)in patients aged 70 and over.The incidence of urinary stone formation was 12.2%(65/532)in patients with components of metabolic syndrome after nephrectomy and 19.7%(42/213)in patients with metabolic syndrome, while the incidence was 4.7%(24/516)in patients without components of metabolic syndrome.In patients with history of urolithiasis, the incidence was up to 30.5%(50/164)after nephrectomy, while 4.4%(39/884)in patients without history of urolithiasis.
ConclusionsThe incidence of urinary stone formation in the contralateral kidney of uninephrectomy patients was higher, especially in patients with metabolic syndrome or urolithiasis history.Patients after unilateral nephrectomy are more vulnerable to urolithiasis.
Key words:
Uninephrectomy; Urolithiasis; Incidence; Metabolic syndrome
Contributor Information
Tianpeng Xie
Department of Urology, First Affiliated Hospital of Gannan Medical University, Jiangxi Engineering Research Center for Prevention and Treatment of Urolithiasis, Ganzhou 341000, China
Qingquan Xu
Xiaobo Huang
Xiaofeng Zou
Guoxi Zhang
Liulin Xiong
Kai Ma
Yuanhu Yuan
Rihai Xiao
Xiaoning Wang
Haiyun Ye
Lizhe An
