Large Cohort Study
A prospective cohort study on the duration of sleep and risk of all-cause mortality among patients with type 2 diabetes
Yijia Chen, Jian Su, Yu Qin, Ying Li, Enchun Pan, Yan Gao, Ning Zhang, Jinyi Zhou, Xiaojin Yu, Ming Wu, Chong Shen
Published 2019-04-10
Cite as Chin J Epidemiol, 2019, 40(4): 394-399. DOI: 10.3760/cma.j.issn.0254-6450.2019.04.005
Abstract
ObjectiveTo investigate the relationship between duration of sleep and all-cause mortality in patients with type 2 diabetes.
MethodsA total of 17 452 type 2 diabetic patients who were under the National Basic Public Health Service Project, in Changshu county, Qinghe district and Huai’an district in Huai’an city of Jiangsu province, were recruited as participants. Cox proportional hazards regression models were used to estimate the associations between different levels on the duration of sleep and all-cause mortality. Stratified analysis was performed according to factors as gender, age, and lifestyle.
ResultsAmong the 67 912 person-years of observation, from the fo1low- up program, the median time of follow-up was 4 years, with 1 057 deaths occurred during the follow-up period. Taking patients with duration of sleep as 7 h/d for reference, the multivariate adjusted hazard ratios (95%CI) of all-cause mortality appeared as ≤6, 8, 9 and ≥10 h/d were 1.14 (0.94-1.37), 1.10 (0.91-1.32), 1.33 (1.05-1.70), and 1.52 (1.24-1.87), respectively which were associated with the duration of sleep. Data from the subgroup analysis showed that this was consistent with the whole population. Longer duration of sleep was associated with the all-cause mortality but no significant association was found between shorter duration of sleep and the all-cause mortality.
ConclusionLonger duration of sleep seemed to have increased the risk of all-cause mortality in type 2 diabetic patients.
Key words:
Diabetes mellitus, type 2; Sleep duration; Mortality; Prospective study
Contributor Information
Yijia Chen
School of Public Health, Southeast University, Nanjing 210009, China
Jian Su
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
Yu Qin
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
Ying Li
School of Public Health, Southeast University, Nanjing 210009, China
Enchun Pan
Huai’an City Center for Disease Control and Prevention of Jiangsu Province, Huai’an 223001, China
Yan Gao
Suzhou City Center for Disease Control and Prevention, Suzhou 215004, China
Ning Zhang
Changshu City Center for Disease Control and Prevention of Jiangsu Province, Changshu 215500, China
Jinyi Zhou
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
Xiaojin Yu
School of Public Health, Southeast University, Nanjing 210009, China
Ming Wu
School of Public Health, Southeast University, Nanjing 210009, China
Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China
Chong Shen
School of Public Health, Nanjing Medical University, Nanjing 211166, China
