China Kadoorie Biobank Study
Association between tea consumption and all-cause mortality in Chinese adults
Nie Jia, Chen Lu, Yu Canqing, Guo Yu, Pei Pei, Chen Junshi, Chen Zhengming, Lyu Jun, Li Liming
Published 2022-02-10
Cite as Chin J Epidemiol, 2022, 43(2): 145-153. DOI: 10.3760/cma.j.cn112338-20201201-01369
Abstract
ObjectiveTo investigate the association between tea consumption and the risk of all-cause and cause-specific mortality among Chinese adults.
MethodsThis study was based on China Kadoorie Biobank (CKB). Tea consumption information was self-reported by participants at baseline. Death was mainly identified by linkage to the death registry system. Cox proportional hazard regression models estimated HR and 95%CI.
ResultsWith a median follow-up of 11.1 years, there were 34 661 deaths in 438 443 participants. Compared with those who never drink tea, all-cause mortality HR(95%CI) were 0.89(0.86-0.91) and 0.92(0.88-0.95) for non-daily tea drinkers and daily tea drinkers, respectively. A statistically significant difference was found in the association of tea consumption and the risk of all-cause mortality between men and women(interaction P<0.05). The protective effect was mainly seen in men. Compared with those who never drink tea, daily tea drinkers had a reduced risk of death from ischemic heart disease, ischemic stroke, hemorrhagic stroke, cancer, respiration diseases and other causes of death, and the corresponding HR(95%CI) were 0.83(0.76-0.92), 0.82(0.69-0.97), 0.86(0.78-0.94), 1.03(0.97-1.09), 1.00(0.87-1.16), 0.84(0.78-0.90). Among never smokers and non-excessive drinkers, there was no statistically significant association between daily tea drinking and the risk of death from cancer. While smokers and excessive drinkers had an increased risk of death from cancer (interaction P<0.001).
ConclusionsTea consumers had reduced risks of all-cause mortality and partial cause-specific mortality, but not for the risk of death from cancer. On the contrary, daily tea drinkers with smoking habits and excessive alcohol drinking had an increased risk of death from cancer.
Key words:
Tea consumption; Mortality; Prospective study; Chinese
Contributor Information
Nie Jia
Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness and Response/Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education,Beijing 100191, China
Chen Lu
Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness and Response/Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education,Beijing 100191, China
Yu Canqing
Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness and Response/Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education,Beijing 100191, China
Guo Yu
Fuwai Hospital Chinese Academy of Medical Sciences, National Center for Cardiovascular Diseases, Beijing 100037, China
Pei Pei
Chinese Academy of Medical Sciences, Beijing 100730, China
Chen Junshi
China National Center for Food Safety Risk Assessment, Beijing 100022, China
Chen Zhengming
Nuffield Department of Population Health, Center for Clinical and Epidemiological Studies/Population Health Research Unit, Medical Research Council, University of Oxford, Oxford OX3 7LF, UK
Lyu Jun
Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness and Response/Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education,Beijing 100191, China
Li Liming
Department of Epidemiology and Biostatistics, School of Public Health, Peking University/Peking University Center for Public Health and Epidemic Preparedness and Response/Key Laboratory of Molecular Cardiovascular Sciences (Peking University), Ministry of Education,Beijing 100191, China
