Original Article
Diagnosis analysis and perinatal management of the 358 fetal congenital heart diseases in single center
Jing Chen, Yanqiu Ou, Fengzhen Han, Jian Zhuang
Published 2018-01-25
Cite as Chin J Thorac Cardiovasc Surg, 2018, 34(1): 13-16,21. DOI: 10.3760/cma.j.issn.1001-4497.2018.01.004
Abstract
ObjectiveTo retrospectively analyze the diagnosis and perinatal management of fetal congenital heart disease(CHD) in our hospital during the past eight years.
MethodsA retrospective analysis of 358 cases of CHD diagnosed by fetal echocardiography prenatal and/or postnatal was done in Guangdong General Hospital from Jan 2006 to Dec 2013, the delivery conditions of these fetus were analyzed.
ResultsIncidence of CHD was 1.85%(358/19 338), 297 cases were prenatal diagnosed, 61 cases were postnatal diagnosed. In the prenatal diagnosed group, 60.6%(180/297)were complex CHD. In the postnatal diagnosed group, 90.2%(55/61) were simple CHD. In the complex CHD, 96.8%(180/186) were prenatal diagnosed. In the prenatal diagnosed group, the survival rate was 68.35%(203/297), of which the simple CHD was 93.16%(109/117), the complex CHD was 52.22%(94/180). The vaginal delivery rate(46.3% vs 42.6%) in the prenatal diagnosed group was higher than the postnatal diagnosed group, the difference was significant(P<0.001).
ConclusionThrough standardized screening and diagnosis methods, most of the complex CHD and part of simple CHD can be prenatal diagnosed. Except for obstetric indications, vaginal delivery was suggested for all of CHD, delivery way did not affect the prognosis. Most of postnatal diagnosed CHD were simple CHD, the prognosis was good. Integrated pattern of prenatal diagnosis and postnatal treatment was completely feasible.
Key words:
Congenital heart defect; Diagnosis
Contributor Information
Jing Chen
Department of Obstetrics, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510080, China
Yanqiu Ou
Department of Epidemiology, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510080, China
Fengzhen Han
Department of Obstetrics, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510080, China
Jian Zhuang
Department of Cardiac Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510080, China
