Original Article
Epidemiology and etiology of hand, foot and mouth disease in Hunan province, 2008-2017
Wei Huang, Yu Chen, Kaiwei Luo, Shanlu Zhao, Fan Zhang, Shuaifeng Zhou, Hong Zhang, Zhifei Zhan
Published 2019-02-28
Cite as Chinese J Exp Clin Virol, 2019, 33(1): 16-20. DOI: 10.3760/cma.j.issn.1003-9279.2019.01.004
Abstract
ObjectiveTo understand the epidemiologic characteristics and pathogen spectrum of hand, foot and mouth disease (HFMD) in Hunan Province during 2008—2017 and provide the basis for the prevention and control strategy of hand, foot and mouth disease.
MethodsCollecting data from national disease reporting information system throughout 2008—2017, the descriptive epidemiological method were used to analyze the data of HFMD monitoring and the result of pathogenic agent detection.
ResultsA total of 1, 255, 530 HFMD cases were reported throughout 2008—2017, including 10097 severe cases and 394 deaths. The average annual attack rate is 190.38/100, 000. The peak incidence of HFMD occurred in summer and fall. The reported incidence is on the rise. The number of critically ill and the number of deaths is declining. Proportion of male cases was higher than that of females. The majority of the children were those under 5 years of age. Enterovirus (EV)-A71, coxsackievirus (CV)-A16 and other other EV positive cases accounted for 33.29%, 20.04% and 46.67% of laboratory diagnosed cases.
ConclusionsThe epidemic of hand, foot and mouth disease in Hunan has obvious seasonal and population characteristics. There are different dominant pathogens causing HFMD in different years.
Key words:
Hand, foot and mouth disease; Epidemiological methods; Etiology
Contributor Information
Wei Huang
Department of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
Yu Chen
Department of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
Kaiwei Luo
Department of Epidemiological Investigation, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
Shanlu Zhao
Department of Epidemiological Investigation, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
Fan Zhang
Department of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
Shuaifeng Zhou
Department of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
Hong Zhang
Department of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
Zhifei Zhan
Department of Microbiology, Hunan Provincial Center for Disease Control and Prevention, Changsha 410005, China
