COVID-19 Prevention and Control
Comparison of results of nucleic acid detection between anal swabs and nasal swabs in confirmed cases of COVID-19
Cai Kanru, Zhang Jieyun, Peng Yabo, Yang Qianting, Zhu Xiuyun, Liu Xunuo, Ma Yunjian, Zhang Mingxia
Published 2021-12-30
Cite as Chinese J Exp Clin Virol, 2021, 35(6): 655-657. DOI: 10.3760/cma.j.cn112866-20200317-00072
Abstract
ObjectiveTo compare the result of nucleic acid detection between anal swabs and nasal swabs in confirmed cases of COVID-19.
MethodsThe result of nucleic acid detection between anal swabs and nasal swabs collected simultaneously at various time points after illness onset were analyzed retrospectively.
ResultsTotally, 46 matched result of anal swabs and nasal swabs in confirmed cases of COVID-19 collected at various intervals after illness onset in 31 patients were analyzed. All the result of nucleic acid detection were positive for anal swabs. The highest concordance rate of nucleic acid positive of COVID-19 (80%) between anal swabs and nasal swabs was observed 0-3 days after illness onset; while the value declined to 28.57% ≥16 days after illness onset. The longer the interval between sampling and illness onset, the lower the concordance rate.
ConclusionsBesides two negative result from respiratory tract specimens, the negative result of anal swabs should be added as an important reference of releasing from quarantine.
Key words:
COVID-19; Anal swabs; Nasal swabs; Nucleic acid
Contributor Information
Cai Kanru
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
Zhang Jieyun
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
Peng Yabo
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
Yang Qianting
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
Zhu Xiuyun
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
Liu Xunuo
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
Ma Yunjian
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
Zhang Mingxia
Institute of Hepatology, Shenzhen Third People’s Hospital, Shenzhen 518000, China
