Abdominal Tumors
Clinicopathological analysis of primary non-Hodgkin’s lymphoma of the female reproductive system
Xiaorong Hou, Xiaoyan Chang, Jie Chen, Ke Hu, Fuquan Zhang
Published 2018-02-15
Cite as Chin J Radiat Oncol, 2018, 27(2): 161-164. DOI: 10.3760/cma.j.issn.1004-4221.2018.02.008
Abstract
ObjectiveTo retrospectively analyze the clinical pathological features and treatment outcomes of primary non-Hodgkin’slymphoma (NHL) of the female reproductive system.
MethodsA retrospective analysis was performed on the clinical data of 28 patients with primary NHL of the female reproductive system who were admitted to our hospital from 1990 to 2016. The lymphomas were classified and staged based on the WHO histological classification and the Ann Arbor staging system, respectively. Of the 28 patients, 18(64%) underwent surgery, 27(96%) received chemotherapy, and 8(29%) received radiotherapy. The Kaplan-Meier method was used to calculate survival rates.
ResultsThe 5-year follow-up rate was 86%.The median age was 56.5 years (13-80 years). The ovary was involved in 11 patients (39%). The lymphoma was staged as IVE in 18 patients (64%). The most common pathological type was diffuse large B-cell lymphoma. The median survival time was 23.5 months. The 1-, 3-, and 5-year overall survival rates were 89%, 74%, and 59%, respectively.
ConclusionsPrimary NLH of the female reproductive system is an extremely rare neoplastic disorder with no typical clinical symptoms and mostly diagnosed in advanced stage. The combined treatment with surgery, chemotherapy, and radiotherapy plays an important role in the treatment of the disorder.
Key words:
Pelvic lymphoma; Female genital system; Non-Hodgkin lymphoma; Prognosis
Contributor Information
Xiaorong Hou
Department of Radiation Oncology, Peking Union Hospital, Chines Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China
Xiaoyan Chang
Department of Pathology, Peking Union Hospital, Chines Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China
Jie Chen
Department of Pathology, Peking Union Hospital, Chines Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China
Ke Hu
Department of Radiation Oncology, Peking Union Hospital, Chines Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China
Fuquan Zhang
Department of Radiation Oncology, Peking Union Hospital, Chines Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China