Since the 21^st century, with the changes of people′s living habits and the aggravation ofenvironmental pollution, the incidence of tumors has been increasing day by day, which has become the main deathcauseof human diseases. Atpresent, in addition to the three major conventional treatments of tumors, the emergence of hyperthermia provides a safer and more effective solution for the prevention and treatment of tumors. Attributed to the rapid development of mechanical manufacturing, computertechnology, molecularbiology, materials science and other disciplines, precision hyperthermia presented by radiofrequency and ultrasonic focusing hyperthermia guided by magnetic resonance imaging (MRI) non-invasive temperature measure technology, as well as molecular level targeted hyperthermia have provided a broader perspective for the treatment of tumors. This article reviews the partial research progress on precision hyperthermia to understand the current general situation of precision hyperthermia for tumors.