To assess the association between sleep quality and depression symptom in patients with type 2 diabetes mellitus (T2DM) in communities.

Thirty-seven communities in Xuzhou city were taken out by cluster sampling in the survey. The patients who met with the criteria were included in the study. Each subject completed a version of a self-designed questionnaire, and the Pittsburgh Sleep Quality Index (PSQI), Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS). Glycosylated hemoglobin A1c (HbA1c) were measured. The patients were grouped according to having sleep problem or depression symptomor not. An independent-samples t-test or chi-square test was used to analyse differences between two groups. Spearman correlation was used for analysis of relationship. Multiple logistic regression analysis was used to examine the relationships between sleep quality and depression.

A total of 1 000 eligible T2DM patients were invited into the study. Overall, 979 T2DM patients were involved in the study. 34.42% (337/979) of T2DM patients were poor sleepers according to their PSQI scores. The rate of depression symptom was 40.96%(401/979). The rate of depression symptom was 31.93%(205/642) in T2DM patients with good sleep quality, and 58.16% (196/337) in T2DM patients with poor sleep quality, and difference was significant (χ²=62.87, P<0.01).The score of PSQI had significantly higher SDS (r=0.388, P< 0.01). After adjustment for confounders(such as age, the level of education, household income per month, a longer duration of diabetes, diabetes complications etc), poor sleep quality was positively associated with depression symptom in T2DM patients (OR=1.56, 95% CI 1.13-2.15).

It shows that poor sleep be correlated with the risk of depression symptom in T2DM patient.

Diabetes mellitus, type 2; Sleep; Depression