Objective To retrospectively analyze the general aviation flight accidents,and the related role of human factors such as pilot's gender,age,flight experience,etc.that played in flight accident as well as to provide constructive advices to China general aviation flight safety.Literature resource and selection Relevant literatures on flight safety of general aviation and human factors published at home and abroad.Literature quotation Thirty-eight published literatures were cited.Literature synthesis U.S.general aviation accident and prevention researches in this area were reviewed,and the roles of pilot's gender,age,flight experience and combination of factors in the general aviation accidents were analyzed,and the advices for China general aviation flight safety were put forward.Human factors were accounted as the first factor in U.S.general aviation accidents.More male pilots were involved in fatal accidents than female pilots because of the nature adventure reason; older pilots' flight experiences might partially compensate their work ability reduction due to physiological and psychological shortages,but with the increased risk potential in flying mission,flight management should be further perfected.In addition,weather and environment conditions,pilot's alcohol taking,drug abuse and other factors could contribute to general aviation accidents.Conclusions General aviation of China is about to usher in a stage of rapid development.Learning from domestic and international existing research results and experiences in aviation medicine,specifying medical examination standards and mechanism for general aviation pilots,strengthening the education and training of pilots and establishing a sound system of accident investigation would be fully helpful to reduce China general aviation flying accidents that caused by human factors in future and to improve flight safety level.