To investigate and summarize the MRI characteristics of splenic sclerosing angiomatoid nodular transformation (SANT).

A retrospective analysis of 5 SANT cases were analyzed, in terms of their MRI characteristics and pathological findings.

MRI findings of SANT included: T₁WI presents iso-signal or slightly low signal, all displayed lesions were detected as low signal compared with spleen, but higher than muscle signal on T₂WI, and with speck dots or starlike low signal in the central area, without necrosis and cystic change. The signal was significantly differentiated compared with the spleen on DWI. On chemical shift imaging, 2 cases were showed slightly higher signal on out phase, the others without signal change. On enhanced scan, 4 cases had edge obvious enhancement on arterial phase, inward filling enhancement, and the signal was higher than the spleen, 1 case without arterial phase enhancement, but with mild concentric delayed enhancement. All of the speck dots and starlike areas decreased with time delay, with certain degree enhancement on delayed phase.

There were some MRI features of SANT, preoperative MRI can prompt diagnosis, but final diagnosis depends on pathology.

Splenic neoplasms; Magnetic resonance spectroscopy; Sclerosing angiomatoid nodular transformation