Original Article
Effect of laparoscopic sleeve gastrectomy on obesity and type 2 diabetes mellitus
Wei Yan, Guangzhong Xu, Dexiao Du, Zhipeng Sun, Kai Li, Buhe Amin, Ke Gong, Bin Zhu, Jirun Peng, Nengwei Zhang
Published 2018-04-25
Cite as Chin J Gen Surg, 2018, 33(4): 280-283. DOI: 10.3760/cma.j.issn.1007-631X.2018.04.003
Abstract
ObjectiveTo explore the morbidity of surgery in connection with laparoscopic sleeve gastrectomy (LSG) and its effect on obese T2DM.
Methods106 obese T2DM patientes undergoing LSG were divided into 2 groups in group 1 25 patients did not have oversewing the staple line and group 2 81 patients had the staple line oversewn in order to reduce bleeding.
ResultsThe differences in intraoperative blood loss (35±15) ml vs. (28±18)ml, postoperative recovery time (2.4±0.9)d vs. (2.3±0.9)d, time to taking liquid food (4.7±1.0)d vs. (4.6±1.0)d between two groups were not significant. There were no significant difference of complication between 2 groups (χ2=3.271, P=0.071). Comparing before surgery to 6 month after surgery, the BMI in group 1, was from (39±5) to (29±4) kg/m2; in group 2, from (40±6) to (31±5) kg/m2, FPG in group 1, from (8.4±1.4) to (6.4±1.2) mmol/L; in group 2, from (8.2±2.0) to (6.8±1.5) mmol/L, 2 hour post-meal blood sugar [group 1, (13.2±4.1) to (9.6±3.2) mmol/L; group 2, (12.2±3.2) to (10.6±2.8) mmol/L] and HbA1c (group 1, 7.2%±1.2% to 5.5%±1.1%; group 2, 7.1%±1.1% to 5.9%±1.2%) decreased significantly in both groups (P<0.01). There was 72 (68%) remission cases of T2DM in 106 patients, there were no significant differences of T2DM remission and BMI between 2 groups at 6 months after surgery (P=0.617).
ConclusionsLSG leads to significant weight loss and T2DM control.
Key words:
Diabetes mellitus, type 2; Gastrectomy; Postoperative complications
Contributor Information
Wei Yan
Department of General Surgery, Beijing Shijitan Hospital, Capital Medical Universiy, Beijing 100038, China
Guangzhong Xu
Dexiao Du
Zhipeng Sun
Kai Li
Buhe Amin
Ke Gong
Bin Zhu
Jirun Peng
Nengwei Zhang