Clinicopathological characteristics and risk factors of female breast hyperplasia in different age groups
Fei Wang, Shuohao Shen, Liyuan Liu, Qi Wang, Hongchuan Jiang, Lisong Teng, Zhimin Fan, Cuizhi Geng, Feng Jin, Lili Tang, Jianguo Zhang, Xiang Wang, Shu Wang, Xuening Duan, Lixiang Yu, Fei Zhou, Yujuan Xiang, Shuya Huang, Chao Zheng, Qinye Fu, Dezong Gao, Liang Li, Zhongbing Ma, Qiang Zhang, Zhigang Yu
Abstract
ObjectiveTo analyze clinicopathological characteristics and the potential risk-related factors of female breast hyperplasia in different age groups.
MethodFrom Jan 2015 to Dec 2016, patients diagnosed with breast hyperplasia in 12 hospitals were evaluated. All patients completed the self-designed questionnaires on women' health, including basic demographic information, clinic examination information, radiologic information and pathologic results. The patients were divided into a young group (<45 years old) and an elderly group (from 45 to 75 years old) .
ResultsThere were 3 684 cases of breast hyperplasia, including 2 291 cases in young group and 1 393 cases in elder group, respectively Clinically breast pain type were most commonly observed in both young and older groups (50.3% vs. 42.7%, P <0.001) . While pathological research based on biopsy showed that breast adenopathy were the most common changes in both groups (67.9% vs. 61.7%, P < 0.001) . More breast cancer cases were identified in elder group than that in young group, especially in clinically lump type patients (9.4% vs. 4.2%, P < 0.001) . Compared with elder group, patients in young group have different distribution characteristics regarding to fertility factors, lifestyle factors and psychology scale including anxiety and depression.
ConclusionDistributions of clinicopathological characteristics and risk factors of female breast hyperplasia differ across different age groups.
Key words:
Breast diseases; Age; Pathology, clinical
Contributor Information
Fei Wang
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Shuohao Shen
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Liyuan Liu
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Qi Wang
Breast Disease Center, Guangdong Women and Children Hospital, Guangzhou 511400, China
Hongchuan Jiang
Department of General Surgery, Beijing Chaoyang Hospital, Beijing 100043, China
Lisong Teng
Department of Surgical Oncology, the First Affliated Hospital of Zhejiang University, Hangzhou 310033, China
Zhimin Fan
Department of Breast Surgery, the First Hospital of Jilin University, Changchun 130021, China
Cuizhi Geng
Breast Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China
Feng Jin
Department of Breast Surgery, the First Affiliated Hospital of China Medical University, Shenyang 110001, China
Lili Tang
Department of Breast Disease, Xiangya Hospital Central South University, Changsha 410008, China
Jianguo Zhang
Department of General Surgery, the Second Affiliated Hospital of Harbin Medical University, Harbin 150001, China
Xiang Wang
Department of Breast Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China
Shu Wang
Breast Disease Center, Peking University People's Hospital, Beijing 100044, China
Xuening Duan
Breast Disease Center, Peking University First Hospital, Beijing 100034, China
Lixiang Yu
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Fei Zhou
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Yujuan Xiang
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Shuya Huang
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Chao Zheng
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Qinye Fu
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Dezong Gao
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Liang Li
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Zhongbing Ma
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Qiang Zhang
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
Zhigang Yu
Department of Breast Surgery, the Second Hospital of Shandong University, Jinan 250033, China
