Original Article
Risk factors of delayed gastric emptying and its influence on the prognosis after radical gastrectomy for distant gastric cancer
Wei Shenghong, Wang Yi, Ye Zaisheng, Zeng Yi, Lin Zhenmeng, Lin Zhitao, Chen Shu, Chen Xiaoling, Chen Luchuan
Published 2020-02-25
Cite as Chin J Gen Surg, 2020,35(02): 104-107. DOI: 10.3760/cma.j.issn.1007-631X.2020.02.005
Abstract
ObjectiveTo analyze the risk factor of delayed gastric emptying (DGE) and the impact of DGE on prognosis after radical gastrectomy of distal gastric carcinoma.
MethodsThe clinical and pathological data of 1447 distant gastric cancer patients undergoing gastrectomy from Jul 2007 to Jan 2018 at Fujian Tumour Hospital was analyzed retrospectively.
ResultDGE was found in 101 patients (7.0%), occurring at a median of (6.0±2.1)d after surgery. It was significantly correled with age, diabetes, hypoproteinemia, preoperative pyloric obstruction, operation time, surgical mode, anastomotic procedure, postoperative analgesia(all P<0.05). Multivariate analysis showed that hypoproteinemia, diabetes, pyloric obstruction in preoperative period, surgical mode, postoperative analgesia, anastomotic procedure were independently associated with DGE. The average hospitalization time for DGE was significantly longer than patients with non DGE(16.3±4.2)d vs(8.1±2.1)d, P<0.05.The five-year survival of patients with DGE and non DGE were 54.9% and 54.2% respectively(P>0.05)
ConclusionDGE prolonged hospital stay, but did not influence patients′ prognosis.
Key words:
Stomach neoplasms; Gastric emptying; Risk factors; Prognosis; Gastrectomy
Contributor Information
Wei Shenghong
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Wang Yi
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Ye Zaisheng
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Zeng Yi
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Lin Zhenmeng
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Lin Zhitao
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Chen Shu
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Chen Xiaoling
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China
Chen Luchuan
Department of Gastrointestinal Surgery, Fujian Provincial Tumor Hospital, Fuzhou 350014, China