Original Article
A clinical analysis of 19 patients with hepatic pseudolymphoma
Chenchen Dai, Xiaodong Zhu, Lingli Chen, Yang Zhou, Pengju Xu, Jianjun Zhou
Published 2019-05-28
Cite as Chin J Hepatobiliary Surg, 2019, 25(5): 337-339. DOI: 10.3760/cma.j.issn.1007-8118.2019.05.005
Abstract
ObjectiveTo study the clinical features of hepatic pseudolymphoma.
MethodsA retrospective study was conducted on 19 patients with hepatic pseudolymphoma who were diagnosed and treated at Zhongshan Hospital in Shanghai from June 2013 to December 2017. Eighteen patients were females and one was a male. The mean age was (55±9) years, range 36 to 68 years. This study mainly analyzed the imaging features, treatment and postoperative results.
ResultsAll patients were diagnosed accidentally, and 78.9% patients did not exhibit any evidence of hepatic B viral infection. A monofocal lesion was found in 14 patients and multifocal lesions in 5 patients. Surgical treatment was performed in all the patients. The lesion size was (1.1±0.4)cm (range 0.5~2.4 cm). Ultrasound revealed hypo- or slightly hypo-echogenicity. On MRI, diffusion weighted imaging showed slight hyperintensity or hyperintensity, all lesions manifested as homogeneous and slightly hyperintensity on T2WI and hypointensity on T1WI. Dynamic enhancement pattern, wash in and wash out, degressive and persistent enhancement were observed in 16(55.2%), 12(41.4%), and 1(3.4%) patients, respectively. More than 70% of lesions were diagnosed as malignant tumors on preoperative imaging. During a follow-up of 6~44 months (median: 19 months), no patient developed metastasis or recurrence.
ConclusionsHepatic pseudolymphoma commonly occurred in women with a small sized lesion. Due to the lack of specific clinical manifestations and imaging findings, preoperative diagnosis was difficult. Surgical resection is still the most optimal treatment. The patients usually have favorable prognosis.
Key words:
Liver neoplasms; Diagnosis; Hepatic pseudolymphoma
Contributor Information
Chenchen Dai
Department of Radiology, Zhongshan Hospital, Fudan University
Shanghai Institute of Medical Imaging
Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai 200032, China
Xiaodong Zhu
Department of Liver Surgery &
Transplantation/Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Lingli Chen
Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Yang Zhou
Department of Radiology, Zhongshan Hospital, Fudan University
Shanghai Institute of Medical Imaging
Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai 200032, China
Pengju Xu
Department of Radiology, Zhongshan Hospital, Fudan University
Shanghai Institute of Medical Imaging
Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai 200032, China
Jianjun Zhou
Department of Radiology, Zhongshan Hospital, Fudan University
Shanghai Institute of Medical Imaging
Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai 200032, China
