Objective To discuss the clinical value of digital subtraction angiography(DSA)and interventional therapy in the abdominal exsanguinations including intra-abdominal hemorrhage,retroperitoneal hemorrhage and gastrointestinal hemorrhage secondary to surgery.Method From June 2003 to June 2009,a total of 24 patients with doubtful abdominal exsanguinations underwent DSA examination and received interventional therapy.The imaging of DSA and the efficacy were retrospectively analyzed.The hemoglobin,hemtocdt,blood pressure,and heart rate before and 3 days after operation were compared.The measurement data were analyzed using pairedsamples t-test,and the SPSS version 11.0 software was used for statistical analysis.Results The diagnosis of causes and site of post-opelative bleeding were entirely depended upon DSA examinations.All the patients accepted interventional therapy in the same session.Twenty-two patients(92%,95%C1:63%～99%)got rid of bleeding immediately without recurrence in 30 days,and two patients underwent re-surgical intervention because of bleedins recurrence within 24 hours.There were no complications of intervention found.The increases in levels of hemoglobin,hematocrit and blood pressures were observed(t=7.564,P=0.000;t=6.616,P=0.000;t=6.051,P=0.000;andt=8.579,P=0.000,respectively),and the heart rate was decreased(t=11.050,P=0.000).Conclusioms The DSAcandetennine the causesand the sites of post-operative bleeding,and the intervenfionai therapy is safe and effective with great clinical values,being worthy to extending in a large scale of application.