Management and outcomes of patients with ST-elevation myocardial infarction in Liaoning province
ZHANG Bo, ZHOU Xu-chen, LIU Jun, ZHU Hao, SUN Yu-jiao, REN Li-na, GAO Yuan, LI Yu-ze, QI Guo-xian
Published 2012-12-11
Cite as Chin J Gen Pract, 2012,11(12): 902-906. DOI: 10.3760/cma.j.issn.1671-7368.2012.12.008
Abstract
Objective To analyze the management and outcomes of patients with ST-segment elevation myocardial infarction (STEMI) in Liaoning province.Methods The data were collected from a prospective and multicenter registry study including 8 tertiary hospitals and 12 secondary hospitals in Liaoning province.Total 1429 patients with acute STEMI admitted to hospitals from June 2009 to June 2010 were included in the study.A unified follow-up questionnaire was applied on patient discharged.Results The average age of patients was (63 ± 13)years.37.4% of patients recognized the disease as heart disease and 39.7% were transported by emergency ambulance with a median symptom-to-door time of 150 min.52.9% patients underwent emergency reperfusion therapy,including fibrinolytic therapy (24.4%) and primary percutaneous coronary intervention (PCI,28.1%).The in-hospital treatment included aspirin (99.6%),clopidogrel (81.9%),statins (90.1%),low molecular weight heparin (89.5%),β-blocker (66.0%),angiotensin converting enzyme inhibitor (ACEI)/ angiotensin receptor blocker (ARB)(66.6%).The in-hospital mortality was 10.7% ; the mortality in females was higher than that in males (18.3% vs.7.9%,P < 0.01) and the mortality in older patients (≥ 65 years) was higher than that in younger patients (<65 years)(17.0% vs.5.2%,P <0.01).The follow-up treatment included:aspirin (81.1%),clopidogrel (45.0%),statins (61.0%),β-blocker (48.3%),ACEI/ARB (42.4%).The follow-up mortality was 5.0% after hospital discharge.Conclusions Longer pre-hospital delay is commonly seen in STEMI patients.There is still certain gap of emergency reperfusion therapy and the evidence-based medication with related clinical guidelines of STEMI management in Liaoning.
Key words:
Myocardial infarction; Myocardial reperfusion; Therapy; Cross-sectional studies
Contributor Information
ZHANG Bo
Department of Cardiology, First Affiliated Hospital, Dalian Medical University, 116011, China
ZHOU Xu-chen
Department of Cardiology, First Affiliated Hospital, Dalian Medical University, 116011, China
LIU Jun
Department of Cardiology, First Affiliated Hospital, Dalian Medical University, 116011, China
ZHU Hao
Department of Cardiology, First Affiliated Hospital, Dalian Medical University, 116011, China
SUN Yu-jiao
Department of Cardiology,First Affiliated Hospital,China medical University Shenyang 11001,China
REN Li-na
Department of Cardiology,First Affiliated Hospital,China medical University Shenyang 11001,China
GAO Yuan
Department of Cardiology,First Affiliated Hospital,China medical University Shenyang 11001,China
LI Yu-ze
Department of Cardiology,First Affiliated Hospital,China medical University Shenyang 11001,China
QI Guo-xian
Department of Cardiology,First Affiliated Hospital,China medical University Shenyang 11001,China