Clinical features of children with early-onset benign occipital epilepsy and late-onset children with benign occipital epilepsy and their EEG changes, treatments and prognoses
SHAN Qiao, LI Pei-dong, LIU Quan, WU Jian-heng, WU Yue-hui, WANG Zhen, XIE Jing-wei
Published 2013-07-15
Cite as Chin J Neuromed, 2013,12(07): 696-699. DOI: 10.3760/cma.j.issn.1671-8925.2013.07.011
Abstract
Objective To investigate the clinical features of children with early-onset benign occipital epilepsy (EBOS) and children with late-onset benign occipital epilepsy (LOS) and their EEG changes,treatments and prognoses.Methods Sixty children with benign occipital epilepsy,admitted to our hospital from June 2007 to June 2012,were chosen in our study; their clinical data were retrospectively analyzed.According to the recommendations of the 2001 International League against Epilepsy (ILAE),these patients were divided into EBOS group (n=28) and LOS group (n=32); the clinical manifestations,electroencephalogram (EEG) characteristics,medication effectiveness in the two groups of children were compared.Results No significant difference on gender distribution,febrile convulsion histories and family history of epilepsy was noted between the two groups (P>0.05); however,average ages of onset in the EBOS group were significantly younger than those in the LOS group (P< 0.05),and the onset time,seizure frequency,attack mode,seizures associated symptoms and seizure EEG waveforms in the EBOS group were obviously different as compared with those in the LOS group.Single-drug AED treatment could have control effect in 23 of children in the EBOS group and 12 of children in the LOS group; statistical difference was noted between the two groups (P<0.05).Conclusion The onset time,seizure frequency,attack mode and seizures associated symptoms are obvious different between children with EBOS and LOS,and combined with seizure EEG waveforms,these differences can be used to identify the two.
Key words:
Early-onset children with benign occipital epilepsy; Late-onset benign occipital lobe epilepsy of children; Clinical feature; Electroencephalogram
Contributor Information
SHAN Qiao
Department of Neurosurgery, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
LI Pei-dong
Department of Neurosurgery, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
LIU Quan
Department of Neurosurgery, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
WU Jian-heng
Department of Neurosurgery, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
WU Yue-hui
Department of Neurosurgery, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
WANG Zhen
Department of Neurosurgery, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
XIE Jing-wei
Department of Neurosurgery, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China