Clinical Researches
MR imaging features of intracranial tumors in infants: a report of 12 cases
Lyujin Feng, Xianlong Wang, Huiyan Li, Hao Yu, Shilong Lu, Shanshan Jiang, Zhibo Wen
Published 2015-03-15
Cite as Chin J Neuromed, 2015, 14(3): 282-286. DOI: 10.3760/cma.j.issn.1671-8925.2015.03.014
Abstract
ObjectiveTo explore the MR imaging characteristics of brain tumors in infants to improve the diagnosis and early treatment.
MethodsTwelve infants with brain tumors (less than 1 year old), performed surgery in our hospital from April 2008 to August 2014 and proved by pathology, were collected in our study; the clinical data and MR imaging features were reviewed retrospectively.
ResultsAmong the 12 infants, 4 (33%) had tumors located at the lateral ventricle, 3 (25%) at the cerebral hemisphere, one (8.3%) at the pineal region, one (8.3%) at the suprasellar region, one (8.3%) at the cerebral convexity, one (8.3%) at the cerebellar hemisphere and one (8.3%) at the fourth ventricle. These tumors included immature teratoma (n=3), choroid plexus tumor (n=3), atypical teratoid/rhabdoid tumor (n=2), medulloblastoma (n=1), anaplastic ependymoma (n=1), pilomyxoidastrocytomas (n=1) and infantile fibrosarcoma (n=1). Diversity of MR imaging features was found in different types of brain tumors; tumors as immature teratoma, atypical teratoid/rhabdoid tumor and infantile fibrosarcoma showed mainly mixed signal intensity on T1-weighted images and T2-weighted images, and these tumors displayed heterogeneously enhancement at MR imaging; choroid plexus tumors and medulloblastoma showed isointenseon T1-weighted images and T2-weighted images mostly, and both had obvious enhancement; anaplastic ependymoma showed isointensity signal on T1-weighted images, slightly hyperintenseon T2-weighted images and heterogeneously enhancement; pilomyxoidastrocytomas were hypointenseon T1-weighted images, hyperintenseon T2-weighted images and homogeneous enhancement.
ConclusionsImmature teratomas, choroid plexus tumors and embryonal tumors are common in infants. Supratentorial tumors are mostly found. Typical features are showed in some brian tumors, but part of atypical tumors remain challenging in diagnosis. To improve diagnostic accuracy, imaging data should be accumulated in the future.
Key words:
Intracranial tumor; Infant; Magnetic resonance imaging
Contributor Information
Lyujin Feng
Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, China
Xianlong Wang
Huiyan Li
Hao Yu
Shilong Lu
Shanshan Jiang
Zhibo Wen