To study skull repairing at different times in influencing the nerve functions in patients from the plateau area.

A retrospective analysis of clinical data of 48 patients with decompressive craniectomy, admitted to our hospitals from January 2008 to December 2014, was performed; these patients were divided into early treatment group (given treatment within 3-6 months, group A, n=22), and late treatment group (given treatment over 6 months, group B, n=26); the differences of intracranial blood supply, intracranial vascular by CTA, brain atrophy, neurological rehabilitation, and cognitive functions between the two groups were respectively observed.

Skull repairing side of intracranial blood supply: the preoperative mean velocity of the anterior cerebral artery was (30.0±5.3) cm/s and postoperative mean velocity (48.0±6.2) cm/s, the preoperative mean velocity of the middle cerebral artery was (39.0±3.9) cm/s and postoperative mean velocity (46.0±4.2) cm/s, the preoperative mean velocity of the posterior cerebral artery was (30.0±3.1) cm/s and postoperative mean velocity (38.0±5.1) cm/s in group A; the preoperative mean velocity of the anterior cerebral artery was (29.0±3.7) cm/s and postoperative mean velocity (42.0±4.1) cm/s, the preoperative mean velocity of the middle cerebral artery was (37.0±4.4) cm/s and postoperative mean velocity postoperative (43.0±3.6) cm/s, the preoperative mean velocity of the posterior cerebral artery was (31.0±4.5) cm/s and postoperative mean velocity (35.0±3.5) cm/s in group B; the postoperative intracranial blood supply of group A was much better than that of B group, with significant differences (P<0.05). The brain atrophy of group A was slighter than that of group B, with significant difference (P<0.05): the distance from cerebral cortex to the midcourt line in group A was (5.25±0.71) cm, and that in group B was (4.83±0.63) cm. Neurological rehabilitation: preoperative and postoperative China stroke scale scores of group A were 4.46±0.65 and 3.15±0.43, respectively, while those in group B were 5.89±0.49 and 4.08±0.61, respectively; both preoperative and postoperative scores in A group were higher than those in group B, with significant differences (P<0.05). The preoperative and postoperative mini-mental state examination scores of A group were 16.28±3.23 and 20.11±2.71, respectively, while those in group B were 15.72±1.28 and 18.20±2.91, respectively; both preoperative and postoperative scores in group A were lower than those in group B, with significant differences (P<0.05).

Early bone repair helps the intracranial blood supply, brain atrophy, neurological rehabilitation and recovery of cognitive function in patients from the plateau area.

Plateau area; Skull repairing; Neural function