To verify the effectiveness and safety of domestic neurosurgery medical robot Remebot for the biopsy of intracranial lesions.

Thirteen patients with intracranial lesions having comparatively difficulty in diagnosis in our hospital from January 2016 to May 2016 were randomly selected to robot operation group (n=6) and frame stereotactic group (n=7). In the robot operation group, four marks were pasted to the patient's head for the stereotaxy without frame, while in the frame stereotactic group, the frame should be fixed to the patient's head for the operation. The targets were set at the central of the lesions and the biopsies were performed through targets to the whole lesions. The specimens were sent for pathologic examinations with immunohistochemical staining.

The confirmed diagnostic rate of robot operation group was 6/6: glioblastoma multiforme in 3, oligodendroglioma in one, non-Hodgkin's lymphoma in one and focal cortical dysplasia in one; the confirmed diagnostic rate of the frame stereotactic group was 6/7: glioblastoma multiforme in 2, grade II-III astrocytoma in 2, follicular thyroid carcinoma in one and cerebellum ganglion glioma in one, and the one without confirmed diagnosis was intracranial multiple cystic lesion. The positional accuracy in the robot operation group was 1.48±0.62 (accuracy error: 0.66-2.47 mm) and that in the frame stereotactic group was 1.06±0.49 (accuracy error: 0.50 mm-1.90 mm).

The domestic neurosuregery medical robot Remebot is characteristic by minimal invasive and high positional accuracy. It is quite suitable for frameless stereotactic intracranial lesion biopsy. The surgical planning could be made according to the shape of lesions and the positional accuracy is reached to the requirement of biopsy. Since the procedure of operation could be performed without fixing the frame on patients' head, the pain and fear of patients are reduced in a great deal and the operation is quite easy to be performed. Thus, it's more suitable for the biopsy of intracranial lesions.

Frameless stereotaxy; Neurosurgery medical robot; Non-frame stereotactic surgery; Biopsy