Original Article
Epidemiological characteristics of hepatitis A before and after inclusion of hepatitis A vaccine in expanded program on immunization in Dalian
Yang Yue, Sun Boyu, Zhou Ling, Zhou Yi
Published 2019-02-25
Cite as Int J Virol, 2019,26(1): 63-65. DOI: 10.3760/cma.j.issn.1673-4092.2019.01.018
Abstract
ObjectiveTo compare the epidemiological characteristics of hepatitis A before and after the inclusion of hepatitis A vaccine in Expanded Program on Immunization (EPI) in Dalian.
MethodsThe data of hepatitis A cases from 1998 to 2017 in Dalian were collected. Changes in temporal, spartial and populational distributions of hepatitis A were analyzed.
ResultsA total of 34 693 hepatitis A cases were reported in Dalian from 1998 to 2017. The average annual incidence of hepatitis A was 28.60/100 000. The annual incidence rates decreased from 55.97/100 000 before EPI inclusion to 5.42/100 000 after EPI inclusion (P<0.01). Before EPI inclusion, the proportion of hepatitis A in the second quarter was the highest (44.98%) and the incidence in urban area was 81.31/100 000. Of all occupations, the proportion of unemployed was the highest, accounting for 24.31% of all cases. After EPI inclusion, the proportion of hepatitis A in the first quarter was the highest, accounting for 40.97% and the incidence in rutal area was 7.70/100 000. Of all the occupations, the proportion of farmer was the highest, accounting for 37.88% of all cases.
ConclusionsAfter the Hepatitis A vaccine was included in the EPI in Dalian, epidemic of hepatitis A was well controlled. Surveillance should be enhanced and integrated control strategy should be formulated for vulnerable population.
Key words:
Hepatitis A; Epidemiological characteristics; Immunization program
Contributor Information
Yang Yue
School of Public Health, Dalian Medical University, Dalian 116044, China
Sun Boyu
Graduate School of Heilongjiang University of Chinese Medicine, Harbin 150040, China
Zhou Ling
School of Public Health, Dalian Medical University, Dalian 116044, China
Zhou Yi
Department of Prevention and Control of Natural Focus Infectious Disease, Center for Disease Control and Provention of Dalian, Dalian 116021, China