Original Article
Risk factor analysis of early complications after pancreaticoduodenectomy
Wang Likun, Kuang Ming, Hua Yunpeng, Chen Bin, He Qiang, Wang Qian, Liang Lijian, Peng Baogang
Published 2019-09-15
Cite as Int J Surg, 2019,46(9): 626-630. DOI: 10.3760/cma.j.issn.1673-4203.2019.09.013
Abstract
ObjectiveTo analyse of risk factors for early complications after pancreaticoduodenectomy.
MethodsRetrospective analysis of 280 cases of pancreaticoduodenectomy in the First Affiliated Hospital, Sun Yat-sen University from January 1999 to October 2009, including 175 males and 105 females; the average age was 57 years, the range is 19 to 81 years old. Observe the perioperative condition and postoperative complications of the patient. Logistic regression analysis was used to analyze risk factors associated with early postoperative complications.
ResultsAmong the 280 patients, 81.1% had preoperative jaundice with obstructive jaundice, the median operation time was 5.5 h. the intraoperative blood loss was (558.0±35.0) ml, 16 patients underwent multiple organ resection. The total postoperative complications was 31.1%. Common postoperative complications were abdominal infection/abscess (10.4%), hemorrhage (7.1%), and pancreatic fistula (2.1%). The pancreaticoenterostomy was mainly performed with a nested end-to-end anastomosis (87.1%) and a bundled pancreaticojejunostomy (7.9%). Logistic regression analysis showed that age, comorbidity, jaundice, preoperative yellowing, pancreatic texture, pancreatic duct placement, prophylactic application of somatostatin, combined organ resection and pancreaticojejunostomy were not predictor of major postoperative complications.
ConclusionsThe incidence of early abdominal complication after pancreaticoduodenectomy is high. There is no significant correlation between the common risk factors in perioperative period and the occurrence of serious complications in the early postoperative period.
Key words:
Pancreatoduodenectomy; Postoperative complications; Risk factor; Mortality
Contributor Information
Wang Likun
Department of General Surgery, Fourth Affiliated Hospital of Anhui Medical University, Hefei 230012, China
Kuang Ming
Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
Hua Yunpeng
Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
Chen Bin
Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
He Qiang
Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
Wang Qian
Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
Liang Lijian
Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
Peng Baogang
Department of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China