Objective To explore the application of hysteroscopy in women with inferlitily who failed in IVF-ET. Methods The clinical data of 86 cases of infertility patientients failed in IVF-ET in our Hospitall by using hysteroscopy were analysed between Jan and Dec. Results The incidence of uterine of 86 infertility patients was 66. 8%. The occurrence of uterine anormality in primary infrttility who failed IVF-ET was 61.54%,the secondary infertility patients was 73.53 %. The common disease was endometrial polpy, endometritis and uterine adhesion. Conclusion The rate of pathological changs of uterine cavity is high in infertility who failed in IVF-ET which is one of important infertile factors. Hysteroscopy has perfound useness in infertility clinic.