Original Article
Infection status and related factors of Helicobacter pylori in Shizuishan Ningxia
Jinpeng Hu, Xiaoping Lu, Lirong Mo, Yan Zhou, Jinfang Yang, Min Niu, Zhen Yang, Xue Zhang, Yanjie You, Feihu Bai
Published 2019-08-25
Cite as China Clin Pract Med, 2019, 10(4): 30-36. DOI: 10.3760/cma.j.issn.1673-8799.2019.04.009
Abstract
ObjectiveTo investigate the influence of Helicobacter pylori infection rate and relevant impact factors in Shizuishan area of Ningxia Hui Autonomous Region.
MethodsA total of 710 healthy volunteers were selected by the random number table, including 235 males and 475 females from 5 districts of Shizuishan City, Ningxia Hui Autonomous Region from December 2018 to February 2019 in Ningxia Shizuishan Second People′s Hospital.The volunteers were aged(44.41±13.88)years and ranging from 14 to 88 years.All volunteers filled in Helicobacter pylori questionnaire and accepted a urea 14C breath test at the same time.The final survey results were statistically analyzed.
ResultsThe HP infection rate of 710 volunteers surveyed in the Shizuishan area of Ningxia was 56.8%(403/710), and the male infection rate[62.1%(146/235)]was higher than female[54.1%(257/475)], and the difference was statistically significant(P<0.05). The HP infection rate of volunteers aged 41 to 60 years[63.6%(325/511)]was higher than volunteers under 40 years old[44.4%(52/117)]and over 60 years old[31.7 %(26/82)], (P<0.05). The HP infection rate of the volunteers on the job[59.1%(355/601)]was higher than the non-working volunteers[44.0%(48/109)], and the difference was statistically significant(P<0.05). The HP infection rate of rural volunteers[65.2%(58/89)]was higher than volunteers living in the county[55.6%(345/621)], (P<0.05). The infection rate of volunteers with family income more than 5 000 yuan[52.4%(66/126)]was lower than volunteers′ income less than 3, 000 yuan[58.7%(155/264)]and from 3 000 to 5 000 yuan volunteers[56.9%(182/320)], (P<0.05). The previous or existing gallbladder disease HP infection rate[72.0%(95/132)]was higher than those without gallbladder diseases[53.3%(308/578)], (P<0.05). The HP infection rate of previous or existing cardiovascular disease patients[66.1%(39/59)]was higher than those without cardiovascular disease[55.9%(364/651)], (P<0.05). The HP infection rate in patients without history of gastroscopy[59.2%(303/512)]was higher than previous or current gastroscopy[50.5%(100/198)], (P<0.05). Volunteers′ awareness of HP was 35.5%(252/710). Multivariate analysis show that gender, age, occupation, and whether has a gastroscopy or not were correlated with HP.
ConclusionThe HP infection rate in the Shizuishan area of Ningxia is consistent with the national average infection level.And the HP infection is closely related to age, gender, occupation, living area, family income, previous or existing gallbladder diseases, cardiovascular diseases, and no gastroscopy.It can provide an epidemiological basis for the prevention and treatment of HP in the region.
Key words:
Helicobacter pylori; Questionnaire survey; 14C breath test; Infection rate; Influencing factors
Contributor Information
Jinpeng Hu
Ningxia Medical University, Yinchuan 750001, China
Xiaoping Lu
Department of Gastroenterology, Second People′s Hospital of Shizuishan City, Shizuishan 753000, China
Lirong Mo
Ningxia Medical University, Yinchuan 750001, China
Yan Zhou
Ningxia Medical University, Yinchuan 750001, China
Jinfang Yang
Ningxia Medical University, Yinchuan 750001, China
Min Niu
Ningxia Medical University, Yinchuan 750001, China
Zhen Yang
Ningxia Medical University, Yinchuan 750001, China
Xue Zhang
First clinical medical college of Northwestern University for Nationalities, Yinchuan 750002, China
Yanjie You
Department of Gastroenterology, People′s Hospital of Ningxia, Yinchuan 750002, China
Feihu Bai
Department of Gastroenterology, People′s Hospital of Ningxia, Yinchuan 750002, China
