Original Article
Epidemiology of thyroid nodules and thyroid function in southern mountainous areas of Ningxia Hui Autonomous Region
Ting Wang, Haili Xue, Qingling Lu, Haidong Zhang, Jinlian Wang, Xueru Li, Bing Qi, Zhijie Ma, Xuefeng Ma, Xuhong Hou, Qingyi Sun, Weiping Jia, Lanjie He
Published 2017-04-20
Cite as Chin J Health Manage, 2017, 11(2): 172-176. DOI: 10.3760/cma.j.issn.1674-0815.2017.02.013
Abstract
ObjectiveTo investigate the prevalence of thyroid nodules and thyroid dysfunction in southern mountainouss areas of Ningxia.
MethodsA cross-sectional study was conducted among a representative sample of 10 639 adults in Jingyuan county with a population proportionate sampling method. High-resolution ultrasound was used to examine the thyroid and fasting blood specimens were collected in the morning for measurement of TSH, FT4, FT3. Chi-square test and spearman rank correlation analysis were used for statistical analysis.
ResultsThe prevalence of thyroid nodules was 29.08%, the sex- and age-adjusted rate was 27.17%. The prevalence of thyroid nodules was higher in women than in men (32.68% vs. 24.88%, χ2=76.029 2, P<0.001) and age was positively associated with thyroid nodules (r=0.272, P<0.001). The rate of thyroid dysfunction, subclinical hypothyroidism, subclinical hyperthyroidism, hypothyroidism, hyperthyroidism were 17.39%, 13.00%, 0.42%, 0.96%, 3.01%, respectively. The prevalence of thyroid nodules was higher in abnormal TSH group than in normal TSH group (39.44% vs. 27.24%, χ2=95.624 0, P<0.001). The level of THS, FT3, FT4 in thyroid nodules group differed from control group (Z=-9.144, P<0.001; Z=-6.140, P<0.001; Z=-1.997, P=0.046).
ConclusionThe prevalence of thyroid nodules and thyroid dysfunction were higher in southern mountainous areas of Ningxia. The relationship between thyroid nodules and thyroid function needs further research. We should pay attention to the early screening and diagnosis of thyroid nodules in mountainous areas.
Key words:
Thyroid nodules; Thyroid function; Southern mountains; Prevalence
Contributor Information
Ting Wang
The Outpatient Epartment of Eneral Hospital of Ningxia Medical University, Yinchuan 750004, China
Haili Xue
Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Qingling Lu
Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Haidong Zhang
Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Jinlian Wang
Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Xueru Li
Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Bing Qi
Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Zhijie Ma
Jing Heyuan Township Health Center in Jingyuan County, Ningxia Hui, Autonomous Region, Guyuan 756400, China
Xuefeng Ma
Xinmin Township Health Center in Jingyuan County, Ningxia, Guyuan 756400, China
Xuhong Hou
Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
Qingyi Sun
Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
Weiping Jia
Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
Lanjie He
Qilu Hospital of Shandong University (Qingdao) , Qingdao 266035, China
Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
