Original Article
Epidemiological study of nonalcoholic fatty liver disease in Jingyuan county of Ningxia Autonomous Region
Qingling Lu, Ting Wang, Haidong Zhang, Haili Xue, Jinlian Wang, Daoyan Li, Wei Zhao, Yongli Yang, Chenghu Ma, Xuhong Hou, Qingyi Sun, Weiping Jia, Lanjie He
Published 2018-06-20
Cite as Chin J Health Manage, 2018, 12(3): 237-242. DOI: 10.3760/cma.j.issn.1674-0815.2018.03.009
Abstract
ObjectiveTo investigate the prevalence of nonalcoholic fatty liver disease and the risk factors in Jingyuan county of Ningxia Autonomous Region.
MethodsThe population proportionate sampling method was applied to enroll a representative sample of 10 639 adults in Jingyuan county and the study was conducted using questionnaires and physical examinations. A total of 10 553 people were included in the analysis after excluding those with missing data. High-resolution ultrasound was used to examine the liver and fasting blood was collected in the morning for measurement of blood glucose, blood lipid, and uric acid. The participants were divided into two groups of those with and without nonalcoholic fatty liver disease; the difference in blood biochemical indexes between fatty liver and non-fatty liver groups was compared, and the logistic regression model was used to explore the risk factors affecting the prevalence of fatty liver.
ResultsThe prevalence of nonalcoholic fatty liver disease was 7.60%. The prevalence of thyroid nodules was higher in men than in women (8.60% vs. 6.82%, χ2=11.772, P=0.001). The prevalence rate of fatty liver increased with age (χ2=57.336, P<0.001), the prevalence rates among ≥18 years-<29 years, ≥30 years-<39 years, ≥40 years-<49 years, ≥50 years-<59 years, ≥60 years-<69 years, and above 70 years were 2.92%, 6.50%, 8.81%, 9.59%, 8.08%, and 4.77% respectively. The detection rate of overweight, obesity, abdominal obesity, impaired fasting glucose, impaired glucose tolerance, diabetes, hypertension, hyperuricemia, and dyslipidemia were higher in nonalcoholic fatty liver disease group than in the normal group (P<0.05). Logistic regression analysis showed that nonalcoholic fatty liver disease group had a higher risk for overweight, obesity, abdominal obesity, impaired fasting glucose, impaired glucose tolerance, diabetes, hypertension, hyperurcemia, and dyslipidemia (OR=5.41, 12.45, 2.99, 1.85, 2.05, 3.30, 1.41, 2.23, and 1.98).
ConclusionThe incidence of nonalcoholic fatty liver in Jingyuan county of Ningxia Autonomous Region was higher. The groups of overweight, obesity, abdominal obesity, impaired fasting glucose, impaired glucose tolerance, diabetes, hypertension, hyperuricemia, and dyslipidemia were high risk factors for nonalcoholic fatty liver disease.
Key words:
Fatty liver; Prevalence
Contributor Information
Qingling Lu
Department of Physical Examination, Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Ting Wang
Department of Health Management Center, General Hospital of Ningxia Medical University, Yinchuan 750000, China
Haidong Zhang
Medical Department, Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Haili Xue
Preventive Medicine Department, Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Jinlian Wang
Medical Record Department, Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Daoyan Li
Ultrasonography Department, Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Wei Zhao
Ultrasonography Department, Cardio-Cerebral Vascular Disease Hospital of Ningxia Medical University, Yinchuan 750000, China
Yongli Yang
Liu Panshan Township Health Center in Jingyuan County, Ningxia Province, Guyuan 756400, China
Chenghu Ma
Da Wan Township Health Center in Jingyuan County, Ningxia, Guyuan 756400, China
Xuhong Hou
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
Qingyi Sun
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
Weiping Jia
Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai 200233, China
Lanjie He
Department of Endocrinology, Qilu Hospital of Shandong University, Qingdao 266035, China
