New Technology And Clinical Medicine
Efficacy of bronchoalveolar lavage and positive pressure ventilation in treatment of traumatic atelectasis
Hong Zhifeng, Li Mingxia, Chen Jieyong, Liu Fengxia
Published 2016-08-15
Cite as Chin J Biomed Eng, 2016,22(4): 323-327. DOI: 10.3760/cma.j.issn.1674-1927.2016.04.013
Abstract
ObjectiveTo investigate the clinical efficacy of bronchoalveolar lavage and positive pressure ventilation in treatment of traumatic atelectasis.
MethodsSixty-eight patients with traumatic atelectasis, who were hospitalized in our department between January 2014 and December 2015, were included in the study, and randomly divided into the study group (n=34) and the control group (n=34). The control group received conventional treatment. The study group was given bronchoalveolar lavage on the basis of conventional treatment. The findings of blood gas analysis and the changes of vital signs were recorded before and after treatment. The clinical efficacy in the two groups was compared. The complications related to the bronchoalveolar lavage were recorded. The dyspnea score, tracheal intubation rate, noninvasive ventilation time, invasive ventilation time, ICU stay time, total length of hospital stay, medical costs, and mortality were compared between the two groups.
ResultsAt 3 d after treatment, the evaluation for the clinical efficacy showed that 19 cases were significantly effective (55.9%) , and the total effective rate was 97.1% (33/34) in the study group; 7 were significantly effective (20.6%) , and the total effective rate was 76.5% (26/34) in the control group. The significantly effective rate and total effective rate in the study group were significantly higher than those in the control group (both P<0.05). There were no statisticallysignificant differences in the levels of oxygen partial pressure (PO2) , partial pressure of carbon dioxide (PCO2) , and arterial oxygen saturation (SaO2) between two groups before treatment (all P>0.05). At 1 h and 24 h after treatment, the levels of PO2 and SaO2 in the study group were significantly increased as compared with the control group (all P<0.05). At 3 d after treatment, the PO2 level in the study group was higher than that in the control group (P<0.05) , whereas there was no statistically significant difference in SaO2 level between the two groups (P>0.05). There were no statistically significant differences in the vital signs between the two groups before and after treatment (all P>0.05). No severe treatment-related complications were found in the study group. The dyspnea score at 3 d after treatment, tracheal intubation rate, noninvasive ventilation time, invasive ventilation time, ICU stay time, total length of hospital stay, medical costs, and mortality in the study group were significantly better than those in the control group (all P<0.05) .
ConclusionThe clinical efficacy of bronchoalveolar lavage is satisfactory for the treatment of traumatic atelectasis.
Key words:
Bronchoscopes; Lavage; Atelectasis; Lung injury, acute
Contributor Information
Hong Zhifeng
Department of Critical Care Medicine, Lecong Hospital of Shunde District, Foshan Guangdong 528315, China
Li Mingxia
Chen Jieyong
Liu Fengxia