Research Assembling
Predictors of reperfusion arrhythmia after PCI in patients with acute myocardial infarction: a Meta-analysis
Zhao Xilan, Li Ming, Liu Jizhong, Luo Xiao, Yang Guoli
Published 2018-06-16
Cite as Chin J Mod Nurs, 2018,24(17): 2045-2051. DOI: 10.3760/cma.j.issn.1674-2907.2018.17.013
Abstract
ObjectiveTo explore the predictors of reperfusion arrhythmia (RA) after PCI in patients with acute myocardial infarction (AMI) using Meta-analysis, and to provide evidence for clinical diagnosis and treatment of RA.
MethodsFirstly, the inclusion and exclusion criteria were restricted and the search strategy was planned. The clinical trials that related to emergency PCI treatment in AMI patients and published before 31st December 2016 were included by two researchers in this study by searching PubMed, CINAHL Database, MEDLINE, Web of Science, Cochrane Libraray, CBM, VIP, CNKI and Wanfang Database. After evaluating the quality of the literature, the Review Manager 5.3 software was used for Meta-analysis.
ResultsA total of 10 studies including 13 923 participants were enrolled. The Meta-analysis showed that the risk factors for RA after PCI in AMI patients included: smoking (OR=1.73; 95%CI 1.17-2.56; P<0.01) , TIMI0 flow grade (OR=2.74; 95%CI 2.15-3.49; P<0.01) , inferior MI (OR=4.52; 95%CI 2.47-8.42; P<0.01) , right coronary artery infarction (OR=3.19; 95%CI 1.07-9.58; P=0.04) , multi-vasculopathy (OR=3.05; 95%CI 1.83-5.09; P<0.01) , renal failure (OR=2.81; 95%CI 1.45-5.43; P<0.01) , time from symptom onset to PCI≤6 h (OR=2.41; 95%CI 1.43-4.07; P<0.01) , and duration of operation >1 h (OR=4.03; 95%CI 1.60-10.15; P<0.01) . The protective factors included hypertension history (OR=0.76; 95%CI 0.63-0.93; P<0.01) and pre-infarction angina (OR=0.20; 95%CI 0.13-0.30; P<0.01) . There were no significant differences in age (OR=1.03; 95%CI 0.95-1.11; P=0.48) , history of diabetes (OR=1.26; 95%CI 0.29-5.47; P=0.75) , and Killip grade>1 (OR=2.22; 95%CI 0.90-5.48; P=0.08) .
ConclusionsThe risk factors for RA after PCI in AMI patients include smoking, TIMI0 flow grade, inferior MI, right coronary artery infarction, multi-vasculopathy, renal failure, time from symptom onset to PCI ≤6 h, and duration of operation >1 h. The hypertension history and pre-infarction angina are protective against RA after PCI in AMI patients.
Key words:
Meta-analysis; Myocardial infarction; Percutaneous coronary intervention; Reperfusion arrhythmia; Predictors
Contributor Information
Zhao Xilan
Cardiovascular Medicine Department, the Fuling Center Hospital of Chongqing City, Chongqing 408000, China
Li Ming
Cardiovascular Medicine Department, the Fuling Center Hospital of Chongqing City, Chongqing 408000, China
Liu Jizhong
Nursing Department, the Fuling Center Hospital of Chongqing City, Chongqing 408000, China
Luo Xiao
Nursing Department, the Fuling Center Hospital of Chongqing City, Chongqing 408000, China
Yang Guoli
Nursing Department, the Fuling Center Hospital of Chongqing City, Chongqing 408000, China
