To investigate the clinical status of disease self-management ability in patients with chronic hepatitis B liver fibrosis and to analyze the effect of gratitude, social support and perceived stress on the ability.

Totally 236 patients with chronic hepatitis B liver fibrosis were selected from Guangzhou Red Cross Hospital by convenient sampling from January 2016 to June 2017 and investigated with the general information questionnaire, the Chronic Hepatitis B Self-Management Scale, the Gratitude Resentment and Appreciation Test (GRAT) , the Social Support Rating Scale and the Perceived Stress Scale-Chinese (CPSS) . PASW Statistics 18.0 and AMOS 18.0 were used to analyze the effects.

The disease self-management score in patients with chronic hepatitis B liver fibrosis was (94.41±16.78) . According to correlation analysis, gratitude, social support and perceived stress were positively correlated with disease self-management (r=0.327, 0.339; P<0.05) ; while perceived stress was negatively correlated with disease self-management (r=-0.574, P<0.05) . The multiple linear regression analysis and model fitting showed that gratitude had direct effect on disease self-management (β=0.314) ; social support had direct influence (β=0.354) and indirect (β=0.199) effect on it; and perceived stress had direct (β=-0.567) and indirect (β=-0.058) on it.

The patients with chronic hepatitis B liver fibrosis show a relatively poor disease self-management ability. Clinical medical and nursing staff shall cultivate the patients' gratitude, mobilize their social support, reduce their perceived stress and improve their disease self-management ability.

Hepatitis, B; Liver fibrosis; Disease self-management; Influencing factors; Path analysis