To explore the effects of enhanced recovery nursing on early postoperative vein thromboembolism (VTE) risk after pancreaticoduodenectomy (PD) .

Using convenience sampling method, the 45 cases of PD patients with traditional nursing methods from September 2016 to March 2017 were assigned as the control group, and the 66 cases of PD patients with enhanced recovery nursing from March 2017 to June 2018 were assigned as intervention group. The plasma D-dimer level before operation, immediately after operation, and in different postoperative days (POD) : POD1, POD2, POD3 and POD7 were collected. The D-dimer level and the incidence rates of symptomatic VTE were compared between two groups.

The D-dimer values of the intervention group immediately after surgery, POD1, POD2, POD3 and POD7 were (2.74±2.31) , (3.31±2.03) , (3.98±3.10) , (4.30±2.89) and (7.46±3.90) mg/L·FEU. The D-dimer of the control group at each postoperative time point were (2.88±1.92) , (3.77±2.72) , (4.37±2.70) , (4.08±1.81) and (6.85±4.07) mg/L·FEU. The overall D-dimer value of the two groups showed an upward trend after operation, but there was no significant difference between two groups (P>0.05) . Repeated measures analysis of variance showed that there were no differences in between-group effect (F=0.03, P=0.87) or interaction effect (F=1.01, P=0.38) of D-Dimer, while the difference in intra-group effect was statistically significant (F=108.28, P<0.05) . There was no statistical significance in the difference of the incidence rates of symptomatic VTE between two groups (χ²=0.87, P>0.05) .

The early postoperative VTE risk after PD gradually increased, and the enhanced recovery nursing show no significantly advantage in VTE risk reduction after PD compared to traditional methods.

Vein thromboembolism; Pancreaticoduodenectomy; Enhanced recovery; Thrombus risks; D-dimer; Symptomatic thrombosis