Objective To analyze the clinicopathologic characteristics and prognosis among different age groups patients with breast cancer.Methods The clinical data of 1159 patients in Weihai,who were treated from January 2005 to December 2009,were retrospectively alanyzed.The clinicopatholodic factors and the survival rates among the young group(aged of ＜35 years old at diagnosis),middle-aged group ( ≥35 years old,＜60 years old),the elderly group( ≥60 years old) were compared.Results The median follow-up time was 13.8 months,5-year survival rates were 71.9％,79.7％,76.8％ (P ＜ Q.01).Young group had the highest rate of axillary lymph node metastases (73％),middle-aged group' s ER,PR receptor expression was highest (67.6％ and 63.2％ respectively),the elderly group had biggest tumor at diagnosis.Conclusions Young women showed a higher invasiveness and lymph node metastasis rate,worst 5-year survival rate.The prognosis of middle-aged patients with hormone-dependent breast cancer is,the prognosis the best.In the elderly patients,the prognosis is the medium of the two groups.