To investigate the changes of the levels of serum calcitonin (PCT) and its clinical significance in patients with acute pancreatitis(AP), and to provide reference for clinical diagnosis and treatment of AP patients.

The clinical data of 83 patients with AP from January 2013 to December 2014 were retrospectively analyzed. They were divided into two groups according to different severity of disease, 47 cases in mild acute pancreatitis group (MAP) and 36 cases in severe acute pancreatitis group (MAP), and 50 cases of healthy persons were selected as healthy control group at the same time. The levels of PCT in the three groups were compared.

The CTSI score, BISAP score, APACHEⅡ score in SAP group were higher than those in MAP group (P<0.05); the levels of serum CRP and PCT in SAP group and MAP group were significantly higher than those in control group(P<0.05), and those in SAP group were significantly higher than those in MAP group (P<0.05); the serum PCT levels were significantly lower in the two groups after treatment (P<0.05), and the serum PCT level was significantly higher in the SAP group than that in the MAP group (P<0.05); Pearson correlation analysis showed that PCT, was positively correlated with BISAP score, APACHE score and CTSI score (r>0, P<0.05).

The level of PCT in patients with AP is significantly higher, which can be used as an important index for evaluating the severity of the disease.

Acute pancreatitis; Procalcitonin; Horizontal change; Clinical significance