Specific original articles on breast cancer
The relationship between plasma triglycerides, cholesterol levels and breast cancer
Zhongcheng Gao, Xiaoxia Zhang, Kun Luo, Lixiang Yu, Zhigang Yu, Bo Li
Published 2015-10-25
Cite as Chin J Endocr Surg, 2015, 09(5): 381-384. DOI: 10.3760/cma.j.issn.1674-6090.2015.05.008
Abstract
ObjectiveTo investigate the relationship between plasma triglycerides(TG), cholesterol(TC)levels and breast cancer.
Methods105 cases of breast cancer(age from 22 to 69 years)and 261 cases of healthy control(age from 16 to 52 years)admitted from May. 2014 to Oct. 2014 were studied. TG and TC were tested. Subgroup analysis was performed by age(<35, 35-45, ≥45 years)and BMI(<18.5, 18.5-24, ≥24).
ResultsTG level in breast cancer group was significantly higher than that of the healthy control group(t=-3.97, P=0.00), and TC level was lower than that in the healthy control group(t=2.49, P=0.01). TG level of breast cancer patients≥45 years old was higher than that in the healthy control group(t=-4.31, P=0.00). TC level of breast cancer patients<35 years and from 35 to 45 years was lower than that of the healthy control group(t=3.12, P=0.00及t=2.41, P=0.02); TG levels in breast cancer group were significantly lower than those of the healthy control group for all BMI subgroup(t=-3.67, P=0.01 for BMI<18.5; t=-3.87, P=0.00 for BMI from 18.5 to 24.0; t=-2.01, P=0.04 for BMI≥24). TC level of breast cancer patients was higher than that of the healthy control group for patients whose BMI<18.5(t=-3.41, P=0.01)and it was lower than that of the healthy control group for patients whose BMI≥24.
ConclusionsThe relationship between TG, TC and breast cancer is associated with age. Compared with healthy group, breast cancer patients≥45 years have a higher TG level and breast cancer patients<45 years have a lower TC level.
Key words:
Breast cancer; Triglyceride; Cholesterol
Contributor Information
Zhongcheng Gao
Department of Breast and Thyroid Surgery, Linyi People's Hospital, Linyi 276003, China
Xiaoxia Zhang
Kun Luo
Lixiang Yu
Zhigang Yu
Bo Li
