To explore the diagnosis and management of functional pancreatic endocrine tumor.

Clinical data of 19 cases of functional pancreatic endocrine tumor were retrospectively analyzed.

15 cases of insulinoma, 2 cases of gastrinoma and 2 cases of glucagonoma were qualitatively diagnosed. The positive rate of preoperative diagosis for type B ultrasonic inspection, CT, MRI, EUS, selective portovenous sampling and intraoperative type B ultrasonic inspection was 15.8% (3/19) , 67.5% (10/16) , 71.4% (5/7) , 87.5% (7/8) , 100% (2/2) and 85.7% (6/7) respectively. Of the total 19 cases, 7 cases underwent open surgery, 11 cases underwent laparoscopic surgery, and one case didn’t undergo any surgery as liver metastasis had occurred when glucagonoma was diagnosed. The operation methods included tumor enucleation (n=13) , distal pancreatic resection (n=3) , distal pancreatic resection plus splenectomy (n=1) , and pancreatic head resection with duodenum preserved (n=1) .

The measurement of serum insulin, gastrin and glucagon is the main basis for qualitative diagonosis of pancreatic endocrine tumor. Two stage spinal CT thin scanning is the main method for tumor location. Intraoperative type B ultrasonic inspection is the supplement to preoperative location. Tumor enucleation is the main choice of treatment.

Functional pancreatic endocrine tumor; Pancreatic resection; Laparoscopic surgery