Curcumin is a natural active substance extracted form Curcuma Longa Linn.It can inhibit tumor cell proliferation and induce apoptosis of tumor cells without negative side effects.The mechanisms of its anti-tumor effect include:at gene level,it can inhibit the activation of eukaryotic transcription factor nuclear facor-kappa B,regulate tumor genetic proteins,and withhold the expression of regulatory protein;at cell level,it can induce the arrest of cell cycle and apoptosis;and at tissue level,it can inhibit tumor angiogenesis.Recent research demonstrated its anti-tumor effect in Mimentary canal.It can also inhibit growth and proliferation of human breast cancer MCF-7 cells.In addition,the effectiveness of curcumin in treating nasopharyngeal carcinoma,lung cancer,and prostatic cancer has been reported.