Change of bacteria and enzymes in the drainage fluid in patients with intestinal fistulas
ZHU Jin-guo, YU Ren, PANG Li-qun, TANG Xiao-jun, ZHAO Yao
Published 2011-12-30
Cite as , 2011,19(06): 383-386. DOI: 10.3760/cma.j.issn.1674-635x.2011.06.007
Abstract
Objective To investigate the amount of bacteria and the expression of amylase and lipases in the drainage fluid in patients with intestinal fistulas with time courses.Methods The samples were collected from 16 patients with high intestinal fistulas from July 1998 to January 2008.The amounts of bacteria from the drainage fluid were measured 0,2 and 4 hours after taking out from the patients.At the respective time points,the intestinal juices were also collected to measure the amylase and lipase expressions.After reinfusion of succus entericus,thelevels of albumin,prealbumin,transferring,and fibronectin were measured at 0,7,and 14 days,Results There was no significant increase of bacteria in the drainage fluid within 4 hours ( F(0,2) =18 812.50,P > 0.05 ; F(0,4) =387 625.00,P > 0.05).and there was no change in the expressions of amylase ( F(0,2) =190.60,P > 0.05 ;F(0,4) =631.75,P>0.05) and lipase within 4 hours (F(0,2) =204.10,P>0.05; F(0,4) =1080.05,P>0.05).After succus entericus reinfusion,the fibronectin (F(0,14) =74.24,P < 0.01 ; F(7,14) =59.78,P <0.01),transferring (F(0,14) =0.46,P < 0.01 ; F(7,14) =0.39,P < 0.05 ),and prealbumin ( F(0,14) =54.37,P < 0.05) were increased significantly.Conclusions Bacteria and enzymes do not increase in the drainage fluid within 4 hours in patients with intestinal fistulas.Therefore,it is safe and effective to reinfuse succus entericus.
Key words:
Enteral fistulas; Amount of bacteria; Amylase; Lipases; Succus entericus reinfusion
Contributor Information
ZHU Jin-guo
Department of General Surgery, the First People's Hospital of Huai'an City, Huai'an Jiangsu, 223300, China
YU Ren
Department of General Surgery, the First People's Hospital of Huai'an City, Huai'an Jiangsu, 223300, China
PANG Li-qun
Department of General Surgery, the First People's Hospital of Huai'an City, Huai'an Jiangsu, 223300, China
TANG Xiao-jun
Department of General Surgery, the First People's Hospital of Huai'an City, Huai'an Jiangsu, 223300, China
ZHAO Yao
Department of General Surgery, the First People's Hospital of Huai'an City, Huai'an Jiangsu, 223300, China