Oiginal Article
Impact of nutrition intervention and physical exercise on muscle mass and body fat among community elderly with sarcopenia: a randomized controlled study
Li Wenli, Li Zhuo, Li Chunwei, Cui Min, Yu kang, Xi Yuandi
Published 2022-02-28
Cite as Chin J Clin Nutr, 2022, 30(1): 1-8. DOI: 10.3760/cma.j.cn115822-20211214-00240
Abstract
ObjectiveTo investigate the impact of nutrition supplementation (whey protein, fish oil and vitamin D) and physical exercise (resistance and aerobic exercise) on muscle mass and body fat metrics among community elderly with sarcopenia.
Method102 eligible sarcopenic participants per inclusion and exclusion criteria were randomized into the control group (routine consultation, n=34) or the groups receiving nutrition supplementation (Nutr, n=34) or nutrition supplementation combined with exercise (Nutr+Ex, n=34) for 12 weeks. Muscle and body fat related indicators were compared across groups pre- and post-intervention.
ResultsAnalysis of covariance showed that all indicators were significantly different between groups (all P<0.05). Further pairwise comparisons showed that compared with controls, patients in Nutr group showed increased appendicular muscle mass (ASM) by 0.837 kg (P=0.003, 95% CI: 0.301 to 1.372) and decreased fat mass by 2.876 kg (P<0.01, 95% CI: -3.941 to -1.812), while patients in Nutr+Ex group showed increased ASM by 0.745 kg (P=0.010, 95% CI: 0.180 to 1.311) and decreased fat mass by 2.928kg (P<0.01, 95% CI: -4.408 to -1.808). Other muscle-related indicators also increased while fat-related indicators decreased in both Nutr and Nutr+Ex groups. However, there is no significant difference between Nutr and Nutr+Ex groups.
ConclusionsNutrition supplementation and physical exercise contribute to muscle mass and body fat improvement among sarcopenic elderly. Lifestyle intervention based on nutrition intervention is important for the community elderly with sarcopenia.
Key words:
Sarcopenia; Elderly; Muscle mass; Body fat; Nutrition supplementation; Resistance training
Contributor Information
Li Wenli
School of Public Health, Capital Medical University, Beijing 100069,China
Li Zhuo
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing 100730,China
Li Chunwei
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing 100730,China
Cui Min
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing 100730,China
Yu kang
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Beijing 100730,China
Xi Yuandi
School of Public Health, Capital Medical University, Beijing 100069,China
本文中补充“李文力和李卓对本文有同等贡献”,与本文英摘表述一致,特此更正!