Clinical Sciences
Agreement of intraocular pressure measured by noncontact tonometer and Goldmann applanation tonometer: a Meta-analysis
Ying Wang, Ning Fan, Xizhen Wang, Ningli Wang, Xuyang Liu
Published 2017-04-10
Cite as Chin J Exp Ophthalmol, 2017, 35(4): 339-343. DOI: 10.3760/cma.j.issn.2095-0160.2017.04.011
Abstract
BackgroundNoncontact tonometer (NCT) is a common application in clinical ophthalmology, while its measured value is influenced by corneal parameter.In recent years, there existed some clinical trials discussing the agreement between NCT and gold standard Goldmann applanation tonometer (GAT), but there was still lack of evidence.
ObjectiveThis study was to evaluate the agreement between NCT and GAT by applying evidence based medicine (EBM) method.
MethodsA systematic literature retrieval was conducted from the MEDLINE, EMbase, CBM disc and CNKI database with the limitation of publishing time until June 2016.The literatures were screened according to the inclusion and exclusion criteria.The sample size, average age, sample characteristics and follow-up time were extracted.The value of intraocular pressure measured by NCT and GAT were analyzed.The overall effect size was analyzed using Review Manager 5.3 (from The Cochrane Collaboration) as weighted mean difference (WMD). There existed heterology in this study.Radom effect mode was used to evaluate and compare the difference between NCT and GAT value.
ResultsTwenty four articles were retrieved.Six comparison studies incorporated with 478 eyes were included for Meta analysis.After random effects model was performed for correction.Intraocular pressure measured by NCT was 0.02 mmHg larger than that by GAT (1 mmHg= 0.133 kPa). There was no significant difference in the measurement value of IOP between the two instruments (WMD=0.02, 95%CI: -0.59 to 0.63, P=0.95). Funnel chart method showed that literature publication bias existed in this study.
ConclusionsNormal persons' IOP obtained from NCT and GAT showed a good reproducibility.More comparison studies are needed to support this result.
Key words:
Intraocular pressure; Non-contact tonometer; Goldmann applanation tonometer; Meta-analysis; Evidence-based medicine
Contributor Information
Ying Wang
Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518000, China
Ning Fan
Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Jinan University, Shenzhen 518000, China
Xizhen Wang
Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Jinan University, Shenzhen 518000, China
Ningli Wang
Beijing Institute of Ophthalmology, Beijing Tongren Eye Hospital, Capital Medical University, Beijing 100730, China
Xuyang Liu
Shenzhen Key Laboratory of Ophthalmology, Shenzhen Eye Hospital, Jinan University, Shenzhen 518000, China
