Clinical Science
Association of dominant eye and non-dominant eye with severity of chronic primary angle-closure glaucoma
Chukai Huang, Qiang Wang, Mingzhi Zhang, Lifang Liu, Zhenggen Wu, Di Ma
Published 2020-05-10
Cite as Chin J Exp Ophthalmol, 2020, 38(5): 410-414. DOI: 10.3760/cma.j.cn115989-20200326-00207
Abstract
ObjectiveTo investigate the association of ocular dominance with the severity of chronic primary angle-closure glaucoma (PACG).
MethodsOcular dominance was assessed via the " hole in card" method.The anatomical symmetry (including anterior chamber depth, lens thickness and axial length) in both eyes was analyzed via A scan ultrasound.The severely glaucomatous eye was determined by the mean defect of visual field.The association of ocular dominance with the severity of chronic PACG was then analyzed.This study followed the Declaration of Helsinki, and the study protocol was approved by the Ethics Committee of Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong.Written informed consent was obtained from all subjects prior to their entering the study cohort.
ResultsVisual acuity (LogMAR) was 0.39±0.24 in the dominant eye group, and 0.43±0.29 in the non-dominant eye group.Anterior chamber depth was (2.53±0.26)mm in the dominant eye group, and (2.54±0.29)mm in the non-dominant eye group.Lens thickness was (4.96±0.31)mm in the dominant eye group, and (4.92±0.33)mm in the non-dominant eye group.Axial length was (22.58±0.61)mm in the dominant eye group, and (22.73±1.11)mm in the non-dominant eye group.No significant difference was found in visual acuity, anterior chamber depth, lens thickness or axial length between the dominant and non-dominant eye groups (t=-1.643, -0.797, 1.867, -1.345; all at P>0.05). The vertical cup-disc ratio of the dominant eye group was lower than that of the non-dominant eye group (0.55 [0.40, 0.80]vs. 0.80 [0.63, 0.90]). The mean defect in the visual field of the dominant eye group was lower than that in the non-dominant eye group (-6.54 [-16.70, -3.85]dB vs.-18.77 [-28.19, -8.55]dB), and the intraocular pressure in the dominant eye group was lower than that in the non-dominant eye group (21.00 [17.00, 27.75]mmHg vs. 24.50 [19.00, 36.25]mmHg) (1 mmHg=0.133 kPa). Significant differences were found in mean defect, vertical cup-disc ratio and intraocular pressure between the two groups (Z=-3.781, -3.528, -2.126; all at P<0.05). The ratio of the severely glaucomatous eye being the non-dominant eye was 84.09%, which was much higher than that of the severely glaucomatous eye being the dominant eye (15.91%). The non-dominant eye was related to the severity of chronic PACG (χ2=40.909, P<0.001, Pearson contingency coefficient r=0.563).
ConclusionsThe non-dominant eye is associated with the severity of chronic PACG.
Key words:
Glaucoma; Eye dominance; Severity; Relationship
Contributor Information
Chukai Huang
Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou 515041, China
Qiang Wang
Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou 515041, China
Mingzhi Zhang
Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou 515041, China
Lifang Liu
Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou 515041, China
Zhenggen Wu
Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou 515041, China
Di Ma
Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong, Shantou 515041, China
